The University of Queensland

Virus-encoded 7 transmembrane receptors

Molleskov-Jensen, Ann-Sofie, Oliveira, Martha Trindade, Farrell, Helen Elizabeth and Davis-Poynter, Nick (2015). Virus-encoded 7 transmembrane receptors. The molecular basis of viral infection. (pp. 353-393) edited by P. J. Klasse. Maryland Heights, MO United States: Academic Press. doi: 10.1016/bs.pmbts.2014.10.010

Indirect CD4 ⁺ T cell protection against mouse gamma-herpesvirus infection via interferon gamma

Xie, Wanxiaojie, Bruce, Kimberley, Belz, Gabrielle T., Farrell, Helen E. and Stevenson, Philip G. (2024). Indirect CD4 + T cell protection against mouse gamma-herpesvirus infection via interferon gamma. Journal of Virology. doi: 10.1128/jvi.00493-24

Indirect CD4+ T cell protection against persistent MCMV infection by NK cells requires IFNγ

Xie, Wanxiaojie, Bruce, Kimberley, Stevenson, Philip G. and Farrell, Helen E. (2024). Indirect CD4+ T cell protection against persistent MCMV infection by NK cells requires IFNγ. Journal of General Virology, 105 (1) ARTN 001956. doi: 10.1099/jgv.0.001956

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. mSphere, 8 (3), e0016523. doi: 10.1128/msphere.00165-23

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. Journal of Virology, 97 (5), e0045123. doi: 10.1128/jvi.00451-23

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. mBio, 14 (3), e0081523. doi: 10.1128/mbio.00815-23

The viral G-protein-coupled receptor homologs M33 and US28 promote cardiac dysfunction during murine cytomegalovirus infection

Bonavita, Cassandra M., White, Timothy M., Francis, Joseph, Farrell, Helen E., Davis-Poynter, Nicholas J. and Cardin, Rhonda D. (2023). The viral G-protein-coupled receptor homologs M33 and US28 promote cardiac dysfunction during murine cytomegalovirus infection. Viruses, 15 (3) 711, 1-18. doi: 10.3390/v15030711

Statement in Support of: “Virology under the Microscope-a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope-a Call for Rational Discourse”. Journal of Virology, 97 (5). doi: 10.1128/jvi.00451-23

The CMV-encoded G protein-coupled receptors M33 and US28 play pleiotropic roles in immune evasion and alter host T cell responses

White, Timothy M., Bonavita, Cassandra M., Stanfield, Brent A., Farrell, Helen E., Davis-Poynter, Nicholas J. and Cardin, Rhonda D. (2022). The CMV-encoded G protein-coupled receptors M33 and US28 play pleiotropic roles in immune evasion and alter host T cell responses. Frontiers in Immunology, 13 1047299, 1-17. doi: 10.3389/fimmu.2022.1047299

Recent advancements in understanding primary cytomegalovirus infection in a mouse model

Bruce, Kimberley, Ma, Jiawei, Lawler, Clara, Xie, Wanxiaojie, Stevenson, Philip G. and Farrell, Helen E. (2022). Recent advancements in understanding primary cytomegalovirus infection in a mouse model. Viruses, 14 (9) 1934, 1934. doi: 10.3390/v14091934

CD4 + T cells control murine cytomegalovirus infection indirectly

Xie, Wanxiaojie, Lee, Byungchul, Bruce, Kimberley, Lawler, Clara, Farrell, Helen E. and Stevenson, Philip G. (2022). CD4 + T cells control murine cytomegalovirus infection indirectly. Journal of Virology, 96 (7) e00077-22, e0007722. doi: 10.1128/jvi.00077-22

The mouse cytomegalovirus G protein-coupled receptor homolog, M33, coordinates key features of in vivo Infection via distinct components of its signaling repertoire

Ma, Jiawei, Bruce, Kimberley, Davis-Poynter, Nicholas, Stevenson, Philip G. and Farrell, Helen E. (2022). The mouse cytomegalovirus G protein-coupled receptor homolog, M33, coordinates key features of in vivo Infection via distinct components of its signaling repertoire. Journal of Virology, 96 (4) e01867-21, e0186721. doi: 10.1128/jvi.01867-21

Constitutive signaling by the human cytomegalovirus G protein coupled receptor homologs US28 and UL33 enables trophoblast migration in vitro

Davis-Poynter, Nicholas and Farrell, Helen E. (2022). Constitutive signaling by the human cytomegalovirus G protein coupled receptor homologs US28 and UL33 enables trophoblast migration in vitro. Viruses, 14 (2) 391, 391. doi: 10.3390/v14020391

Olfactory entry promotes herpesvirus recombination

Xie, Wanxiaojie, Bruce, Kimberley, Farrell, Helen E. and Stevenson, Philip G. (2021). Olfactory entry promotes herpesvirus recombination. Journal of Virology, 95 (23) e01555-21, e0155521. doi: 10.1128/jvi.01555-21

A live olfactory MCMV vaccine attenuated for systemic spread, protects against superinfection

Farrell, Helen E., Bruce, Kimberley and Stevenson, Philip G. (2021). A live olfactory MCMV vaccine attenuated for systemic spread, protects against superinfection. Journal of Virology, 95 (21) e01264-21, e0126421. doi: 10.1128/jvi.01264-21

The murine cytomegalovirus MCK-2 facilitates in vivo infection transfer from dendritic cells to salivary gland acinar cells

Ma, Jiawei, Bruce, Kimberley, Stevenson, Philip G. and Farrell, Helen E. (2021). The murine cytomegalovirus MCK-2 facilitates in vivo infection transfer from dendritic cells to salivary gland acinar cells. Journal of Virology, 95 (17) e00693-21, e0069321. doi: 10.1128/jvi.00693-21

Correction: Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells (PLoS ONE (2010) 5:3 (e9681) DOI: 10.1371/journal.pone.0009681)

Snyder, Christopher M., Davis-Poynter, Nicholas, Farrell, Helen E., Allan, Jane E., Bonnett, Elizabeth L., Doom, Carmen M. and Hill, Ann B. (2019). Correction: Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells (PLoS ONE (2010) 5:3 (e9681) DOI: 10.1371/journal.pone.0009681). PLoS One, 14 (12) e0226705. doi: 10.1371/journal.pone.0226705

Murine cytomegalovirus disseminates independently of CX3CR1, CCL2 or its m131/m129 chemokine homologue

Farrell, Helen E., Bruce, Kimberley, Redwood, Alec J. and Stevenson, Philip G. (2019). Murine cytomegalovirus disseminates independently of CX3CR1, CCL2 or its m131/m129 chemokine homologue. Journal of General Virology, 100 (12), 1695-1700. doi: 10.1099/jgv.0.001333

Murine cytomegalovirus spread depends on the infected myeloid cell type

Farrell, Helen E., Bruce, Kimberley, Lawler, Clara and Stevenson, Philip G. (2019). Murine cytomegalovirus spread depends on the infected myeloid cell type. Journal of Virology, 93 (15) e00540-19. doi: 10.1128/jvi.00540-19

Cytomegalovirus host entry and spread

Farrell, Helen E. and Stevenson, Philip G. (2019). Cytomegalovirus host entry and spread. Journal of General Virology, 100 (4) 001230, 545-553. doi: 10.1099/jgv.0.001230

Murine Cytomegalovirus glycoprotein O promotes epithelial cell infection in vivo

Yunis, Joseph, Farrell, Helen E., Bruce, Kimberley, Lawler, Clara, Wyer, Orry, Davis-Poynter, Nicholas, Brizić, Ilija, Jonjić, Stipan, Adler, Barbara and Stevenson, Philip G. (2018). Murine Cytomegalovirus glycoprotein O promotes epithelial cell infection in vivo. Journal of Virology, 93 (3) e01378-18. doi: 10.1128/jvi.01378-18

Human cytomegalovirus US28 allows dendritic cell exit from lymph nodes

Farrell, Helen E., Bruce, Kimberley, Ma, Jiawei, Davis-Poynter, Nicholas and Stevenson, Philip G. (2018). Human cytomegalovirus US28 allows dendritic cell exit from lymph nodes. Journal of General Virology, 99 (11) 001154, 1509-1514. doi: 10.1099/jgv.0.001154

Murine cytomegalovirus degrades MHC class II to colonize the salivary glands

Yunis, Joseph, Farrell, Helen E., Bruce, Kimberley, Lawler, Clara, Sidenius, Stine, Wyer, Orry, Davis-Poynter, Nicholas and Stevenson, Philip G. (2018). Murine cytomegalovirus degrades MHC class II to colonize the salivary glands. PLoS Pathogens, 14 (2) e1006905, 1-17. doi: 10.1371/journal.ppat.1006905

Murine Cytomegalovirus Spreads by Dendritic Cell Recirculation

Farrell, Helen E, Bruce, Kimberley, Lawler, Clara, Oliveira, Martha, Cardin, Rhonda, Davis-Poynter, Nicholas and Stevenson, Philip G (2017). Murine Cytomegalovirus Spreads by Dendritic Cell Recirculation. mBio, 8 (5) e01264-17, 1-13. doi: 10.1128/mBio.01264-17

Type 1 interferons and NK cells limit murine cytomegalovirus escape from the lymph node subcapsular sinus

Farrell, Helen E., Bruce, Kimberley, Lawler, Clara, Cardin, Rhonda D., Davis-Poynter, Nicholas J. and Stevenson, Philip G. (2016). Type 1 interferons and NK cells limit murine cytomegalovirus escape from the lymph node subcapsular sinus. PLoS Pathogens, 12 (12) e1006069, e1006069. doi: 10.1371/journal.ppat.1006069

Luciferase-tagged wild-type and tropism-deficient mouse cytomegaloviruses reveal early dynamics of host colonization following peripheral challenge

Farrell, Helen, Oliveira, Martha, Macdonald, Kate, Yunis, Joseph, Mach, Michae, Bruce, Kimberley, Stevenson, Philip, Cardin, Rhonda and Davis-Poynter, Nicholas (2016). Luciferase-tagged wild-type and tropism-deficient mouse cytomegaloviruses reveal early dynamics of host colonization following peripheral challenge. Journal of General Virology, 97 (12) 000642, 3379-3391. doi: 10.1099/jgv.0.000642

The cytoplasmic C-tail of the mouse cytomegalovirus 7 transmembrane receptor homologue, M78, regulates endocytosis of the receptor and modulates virus replication in different cell types

Davis-Poynter, Nick, Yunis, Joseph and Farrell, Helen E. (2016). The cytoplasmic C-tail of the mouse cytomegalovirus 7 transmembrane receptor homologue, M78, regulates endocytosis of the receptor and modulates virus replication in different cell types. PLoS ONE, 11 (10) e0165066, 353-393. doi: 10.1371/journal.pone.0165066

Murine Cytomegalovirus exploits olfaction to enter new hosts

Farrell, Helen E., Lawler, Clara, Tan, Cindy S. E., MacDonald, Kate, Bruce, Kimberley, Mach, Michael, Davis-Poynter, Nick and Stevenson, Philip G. (2016). Murine Cytomegalovirus exploits olfaction to enter new hosts. mBio, 7 (2) e00251-16, e00251-16.1-e00251-16.10. doi: 10.1128/mBio.00251-16

Alveolar macrophages are a prominent but non-essential target for Murine cytomegalovirus infecting the lungs.

Farrell, Helen E., Lawler, Clara, Oliveira, Martha T., Davis-Poynter, Nick and Stevenson, Philip G. (2016). Alveolar macrophages are a prominent but non-essential target for Murine cytomegalovirus infecting the lungs.. Journal of Virology, 90 (6), 2756-2766. doi: 10.1128/JVI.02856-15

Animal models of human cytomegalovirus congenital infection

Farrell, Helen (2015). Animal models of human cytomegalovirus congenital infection. Microbiology Australia, 36 (4), 196-199. doi: 10.1071/ma15068

Lymph node macrophages restrict murine cytomegalovirus dissemination

Farrell, Helen E., Davis-Poynter, Nick, Bruce, Kimberley, Lawler, Clara, Dolken, Lars, Mach, Michael and Stevenson, Philip G. (2015). Lymph node macrophages restrict murine cytomegalovirus dissemination. Journal of Virology, 89 (14), 7147-7158. doi: 10.1128/JVI.00480-15

Identification of common mechanisms by which human and mouse cytomegalovirus seven-transmembrane receptor homologues contribute to in vivo phenotypes in a mouse model

Farrell, Helen E., Abraham, Alexander M., Cardin, Rhonda D., Molleskov-Jensen, Ann-Sofie, Rosenkilde, Mette M. and Davis-Poynter, Nicholas (2013). Identification of common mechanisms by which human and mouse cytomegalovirus seven-transmembrane receptor homologues contribute to in vivo phenotypes in a mouse model. Journal of Virology, 87 (7), 4112-4117. doi: 10.1128/JVI.03406-12

Partial functional complementation between human and mouse cytomegalovirus chemokine receptor homologues

Farrell, Helen E., Abraham, Alexander M., Cardin, Rhonda D., Sparre-Ulrich, Alexander H., Rosenkilde, Mette M., Spiess, Katja, Jensen, Tine H., Kledal, Thomas N, and Davis-Poynter, Nicholas (2011). Partial functional complementation between human and mouse cytomegalovirus chemokine receptor homologues. Journal of Virology, 85 (12), 6091-6095. doi: 10.1128/JVI.02113-10

The M33 chemokine receptor homolog of murine cytomegalovirus exhibits a differential tissue-specific role during in vivo replication and latency.

Cardin, Rhonda D., Schaefer, Gregory C., Allen, Janelle R., Davis-Poynter, Nicholas J. and Farrell, Helen E. (2009). The M33 chemokine receptor homolog of murine cytomegalovirus exhibits a differential tissue-specific role during in vivo replication and latency.. Journal of Virology, 83 (15), 7590-7601. doi: 10.1128/JVI.00386-09

Analysis of the subcellular trafficking properties of murine cytomegalovirus M78, a 7 transmembrane receptor homologue

Sharp, E. L., Davis-Poynter, N. J. and Farrell, H. E. (2009). Analysis of the subcellular trafficking properties of murine cytomegalovirus M78, a 7 transmembrane receptor homologue. Journal of General Virology, 90 (1), 59-68. doi: 10.1099/vir.0.004853-0

Functional analysis of the murine cytomegalovirus chemokine receptor homologue M33: Ablation of constitutive signaling is associated with an attenuated phenotype in vivo.

Case, R., Sharp, E., Benned-Jensen, T., Rosekilde, M. M., Davis-Poynter, N. J. and Farrell, H. E. (2008). Functional analysis of the murine cytomegalovirus chemokine receptor homologue M33: Ablation of constitutive signaling is associated with an attenuated phenotype in vivo.. Journal of Virology, 82 (4), 1884-1898. doi: 10.1128/JVI.02550-06

Sequence analysis of the equid herpesvirus 2 chemokine receptor homologues E1, ORF74 and E6 demonstrates high sequence divergence between field isolates

Sharp, Emma L., Farrell, Helen E., Borchers, Kerstin, Holmes, Edward C. and Davis-Poynter, Nicholas J. (2007). Sequence analysis of the equid herpesvirus 2 chemokine receptor homologues E1, ORF74 and E6 demonstrates high sequence divergence between field isolates. Journal of General Virology, 88 (9), 2450-2462. doi: 10.1099/vir.0.82942-0

Murine cytomegalovirus (CMV) M33 and human CMV US28 receptors exhibit similar constitutive signaling activities

Waldhoer, Maria, Kledal, Thomas N, Farrell, Helen and Schwartz, Thue W (2002). Murine cytomegalovirus (CMV) M33 and human CMV US28 receptors exhibit similar constitutive signaling activities. Journal of Virology, 76 (16), 8161-8168. doi: 10.1128/JVI.76.16.8161-8168.2002

Function of CMV-encoded MHC class I homologues

Farrell, H., Davis-Poynter, N., Andrews, D. and Degli-Esposti, M. (2002). Function of CMV-encoded MHC class I homologues. Current Topics in Microbiology and Immunology, 269, 131-151.

NK1.1+ Cells and Murine Cytomegalovirus Infection: What Happens In Situ?

Andrews, D. M., Farrell, Helen, Densley, E. H., Scalzo, A. A., Shellam, G. R. and Delgi-Esposti, M. A. (2001). NK1.1+ Cells and Murine Cytomegalovirus Infection: What Happens In Situ?. Journal of Immunology, 166 (3), 1796-1802. doi: 10.4049/jimmunol.166.3.1796

Cytomegalovirus MHC class I homologues and natural killer

Farrell, Helen, Degli-Esposti, Mariapia, Densley, Eloise, Cretney, Erika, Smyth, Mark and Davis-Poynter, Nicholas (2000). Cytomegalovirus MHC class I homologues and natural killer. Microbes and Infection, 2 (5), 521-532. doi: 10.1016/S1286-4579(00)00315-4

Techniques for studying murine natural killer cells in defense against viral infection

Scalzo, A. A., Farrell, H. E. and Kurupiah, G. (2000). Techniques for studying murine natural killer cells in defense against viral infection. Methods in Molecular Biology, 121, 163-177.

Murine cytomegalovirus homologues of cellular immunomodulatory genes

Davis-Poynter, Nicholas J., Degli-Esposti, Mariapia and Farrell, Helen E. (1999). Murine cytomegalovirus homologues of cellular immunomodulatory genes. Intervirology, 42 (5-6), 331-341. doi: 10.1159/000053969

m144, a murine cytomegalovirus (MCMV)-encoded major histocompatibility complex class I homologue, confers tumor resistance to natural killer cell-mediated rejection

Cretney, Erika, Degli-Esposti, Mariapia A., Densley, Eloise H., Farrell, Helen E., Davis-Poynter, Nick J. and Smyth, Mark J. (1999). m144, a murine cytomegalovirus (MCMV)-encoded major histocompatibility complex class I homologue, confers tumor resistance to natural killer cell-mediated rejection. Journal of Experimental Medicine, 190 (3), 435-443. doi: 10.1084/jem.190.3.435

The murine cytomegalovirus chemokine homolog, m131/129, is a determinant of viral pathogenicity

Fleming, Peter, Davis-Poynter, Nicholas, Degli-Esposti, Mariapia, Densley, Eloise, Papadimitriou, John, Shellam, Geoffrey and Farrell, Helen (1999). The murine cytomegalovirus chemokine homolog, m131/129, is a determinant of viral pathogenicity. Journal of Virology, 73 (8), 6800-6809.

Transcriptional analysis of the murine cytomegalovirus HindIII-I region: Identification of a novel immediate early gene region

Hanson, Laura K., Dalton, Bridget L., Karabekian, Zaruhi, Farrell, Helen E., Rawlinson, William D., Sterrnberg, Richard M. and Campbell, Ann E. (1999). Transcriptional analysis of the murine cytomegalovirus HindIII-I region: Identification of a novel immediate early gene region. Virology, 260 (1), 156-164. doi: 10.1006/viro.1999.9796

Cytomegalovirus evasion of natural killer cell responses

Farrell, Helen E., Degli-Esposti, Mariapia A. and Davis-Poynter, Nicholas J. (1999). Cytomegalovirus evasion of natural killer cell responses. Immunological Reviews, 168 (1), 187-197. doi: 10.1111/j.1600-065X.1999.tb01293.x

Inhibition of NK cells by murine CMV-encoded class I MHC homologue m144

Kubota, A., Kubota, S., Farrell, H. E., Davis-Poynter, N. and Takei, F. (1999). Inhibition of NK cells by murine CMV-encoded class I MHC homologue m144. Cellular Immunology, 191 (2), 145-151. doi: 10.1006/cimm.1998.1424

Inhibition of nk cells by murine CMV-encoded class i mhc homologue M144

Kubota, A., Kubota, S., Farrell, H. E., Davis-Poynter, N. and Takei, F. (1998). Inhibition of nk cells by murine CMV-encoded class i mhc homologue M144. Experimental Hematology, 26 (8)

From sabotage to camouflage: viral evasion of cytotoxic T lymphocyte and natural killer cell-mediated immunity

Farrell, H. E. and Davis-Poynter, N. J. (1998). From sabotage to camouflage: viral evasion of cytotoxic T lymphocyte and natural killer cell-mediated immunity. Seminars In Cell & Developmental Biology, 9 (3), 369-378. doi: 10.1006/scdb.1998.0246

Human and murine cytomegalovirus evasion of cytotoxic T lymphocyte and natural killer cell-mediated immune responses

Davis-Poynter, Nicholas J. and Farrell, Helen E. (1998). Human and murine cytomegalovirus evasion of cytotoxic T lymphocyte and natural killer cell-mediated immune responses. Seminars In Virology, 8 (5), 369-376. doi: 10.1006/smvy.1997.0142

A virus decoy for evasion of innate immunity

Farrell, H. (1998). A virus decoy for evasion of innate immunity. Biomedicine and Pharmacotherapy, 52 (1), 46. doi: 10.1016/S0753-3322(97)86245-2

The murine cytomegalovirus (MCMV) homolog of the HCMV phosphotransferase (UL97(pk)) gene

Rawlinson, W.D., Zeng, F., Farrell, H.E., Cunningham, A.L., Scalzo, A.A., Booth, T.W.M. and Scott, G.M. (1997). The murine cytomegalovirus (MCMV) homolog of the HCMV phosphotransferase (UL97(pk)) gene. Virology, 233 (2), 358-363. doi: 10.1006/viro.1997.8593

Inhibition of natural killer cells by a cytomegalovirus MHC class I homologue in vivo

Farrell, H. E., Vally, H., Lynch, D. M., Fleming, P., Shellam, G. R., Scalzo, A. A. and Davis-Poynter, N. J. (1997). Inhibition of natural killer cells by a cytomegalovirus MHC class I homologue in vivo. Nature, 386 (6624), 510-514. doi: 10.1038/386510a0

Identification and characterization of a G protein-coupled receptor homolog encoded by murine cytomegalovirus

Davis-Poynter, Nicholas J., Lynch, Dania M., Vally, Hassan, Shellam, Geoffrey R., Rawlinson, William D., Barrell, Barclay G. and Farrell, Helen E. (1997). Identification and characterization of a G protein-coupled receptor homolog encoded by murine cytomegalovirus. Journal of Virology, 71 (2), 1521-1529.

A mouse cytomegalovirus glycoprotein retains MHC class I complexes in the ERGIC/cis-Golgi compartments

Ziegler, Heike, Thale, Regine, Lucin, Pero, Muranyi, Walter, Flohr, Thomas, Hengel, Hartmut, Farrell, Helen, Rawlinson, William and Koszinowski, Ulrich H. (1997). A mouse cytomegalovirus glycoprotein retains MHC class I complexes in the ERGIC/cis-Golgi compartments. Immunity, 6 (1), 57-66. doi: 10.1016/S1074-7613(00)80242-3

A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface

Klejinen, Maurits F., Huppa, Johannes B., Lucin, Pero, Mukherjee, Siddhartha, Farrell, Helen, Campbell, Ann E., Koszinowski, Ulrich H., Hill, Ann B and Ploegh, Hidde L. (1997). A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface. EMBO Journal, 16 (4), 685-694. doi: 10.1093/emboj/16.4.685

Analysis of the complete DNA sequence of murine cytomegalovirus

Rawlinson, William D., Farrell, Helen E. and Barrell, Barclay G. (1996). Analysis of the complete DNA sequence of murine cytomegalovirus. Journal of Virology, 70 (10), 8833-8849.

Masters of deception: A review of herpes virus immune evasion strategies

Davis-Poynter, N. and Farrell, H. (1996). Masters of deception: A review of herpes virus immune evasion strategies. Immunology and Cell Biology, 74 (6), 513-522. doi: 10.1038/icb.1996.84

Identification, analysis, and evolutionary relationships of the putative murine cytomegalovirus homologs of the human cytomegalovirus UL82 (pp71) and UL83 (pp65) matrix phosphoproteins

Cranmer, Lee D., Clark, Charles L., Morello, Christopher S., Farrell, Helen E., Rawlinson, William D. and Spector, Deborah H. (1996). Identification, analysis, and evolutionary relationships of the putative murine cytomegalovirus homologs of the human cytomegalovirus UL82 (pp71) and UL83 (pp65) matrix phosphoproteins. Journal of Virology, 70 (11), 7929-7939.

Murine cytomegalovirus with a deletion of genes spanning HindIII-J and -I displays altered cell and tissue tropism

Cavanaugh, V.J., Stenberg, R.M., Staley, T.L., Virgin, H.W., MacDonald, M.R., Paetzold, S., Farrell, H.E., Rawlinson, W.D. and Campbell, A.E. (1996). Murine cytomegalovirus with a deletion of genes spanning HindIII-J and -I displays altered cell and tissue tropism. Journal of Virology, 70 (3), 1365-1374.

DNA sequence and transcriptional analysis of the glycoprotein M gene of murine cytomegalovirus

Scalzo, Anthony A., Forbes, Catherine A., Davis-Poynter, Nicholas J., Farrell, Helen E. and Lyons, Paul A. (1995). DNA sequence and transcriptional analysis of the glycoprotein M gene of murine cytomegalovirus. The Journal of General Virology, 76 (11), 2895-2901. doi: 10.1099/0022-1317-76-11-2895

Identification, sequencing and expression of the glycoprotein-L gene of murine cytomegalovirus

Xu, J.K. , Scalzo, A.A. , Lyons, P.A. , Farrell, H.E. , Rawlinson, W.D. and Shellam, G.R. (1994). Identification, sequencing and expression of the glycoprotein-L gene of murine cytomegalovirus. Journal of General Virology, 75 (11), 3235-3240. doi: 10.1099/0022-1317-75-11-3235

Genes in the HindIII J fragment of the murine cytomegalovirus genome are dispensable for growth in cultured cells: Insertion mutagenesis with a lacZ/gpt cassette

Vieira, Jeffrey, Farrell, Helen E., Rawlinson, William D. and Mocarski, Edward S. (1994). Genes in the HindIII J fragment of the murine cytomegalovirus genome are dispensable for growth in cultured cells: Insertion mutagenesis with a lacZ/gpt cassette. Journal of Virology, 68 (8), 4837-4846.

A murine cytomegalovirus-neutralizing monoclonal antibody exhibits autoreactivity and induces tissue damage in vivo

Chapman, A.J. , Farrell, H.E. , Thomas, J.A. , Papadimitriou, J.M. , Garlepp, M.J. , Scalzo, A.A. and Shellam, G.R. (1994). A murine cytomegalovirus-neutralizing monoclonal antibody exhibits autoreactivity and induces tissue damage in vivo. Immunology, 81 (3), 435-443.

Vaccine potential of a herpes simplex virus type 1 mutant with an essential glycoprotein deleted

Farrell, H. E., Mclean, C. S., Harley, C., Efstathiou, S., Inglis, S. and Minson, A. C. (1994). Vaccine potential of a herpes simplex virus type 1 mutant with an essential glycoprotein deleted. Journal of Virology, 68 (2), 927-932.

Molecular and biological characterization of new strains of murine cytomegalovirus isolated from wild mice

Booth, T.W.M. , Scalzo, A.A. , Carrello, C. , Lyons, P.A. , Farrell, H.E. , Singleton, G.R. and Shellam, G.R. (1993). Molecular and biological characterization of new strains of murine cytomegalovirus isolated from wild mice. Archives of Virology, 132 (1-2), 209-220. doi: 10.1007/BF01309855

Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted

Forrester, Audrey, Farrell, Helen, Wilkinson, Gavin, Kaye, Jane, Davis-Poynter, Nicholas and Minson, Tony (1992). Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted. Journal of Virology, 66 (1), 341-348.

Murine anti-cytomegalovirus monoclonal antibodies with autoreactivity

Lawson, C. M., O'Donoghue, H. L., Farrell, H. E., Shellam, G. R. and Reed, W. D. (1991). Murine anti-cytomegalovirus monoclonal antibodies with autoreactivity. Immunology, 72 (3), 426-433.

Protection against murine cytomegalovirus infection by passive transfer of neutralizing and non-neutralizing monoclonal antibodies

Farrell, H.E. and Shellam, G.R. (1991). Protection against murine cytomegalovirus infection by passive transfer of neutralizing and non-neutralizing monoclonal antibodies. Journal of General Virology, 72 (1), 149-156. doi: 10.1099/0022-1317-72-1-149

Characterization of neutralizing monoclonal antibodies to murine cytomegalovirus

Farrell, H.E. and Shellam, G.R. (1990). Characterization of neutralizing monoclonal antibodies to murine cytomegalovirus. Journal of General Virology, 71 (3), 655-664. doi: 10.1099/0022-1317-71-3-655

Immunoblot analysis of the antibody response to murine cytomegalovirus in genetically resistant and susceptible mice

Farrell, H. E. and Shellam, G. R. (1989). Immunoblot analysis of the antibody response to murine cytomegalovirus in genetically resistant and susceptible mice. Journal of General Virology, 70 (10), 2573-2586. doi: 10.1099/0022-1317-70-10-2573

Regulation of natural killer cell activity and interferon production in the rat lung following aerosol challenge

Farrell, H.E. , Holt, P.G. and Shellam, G.R. (1985). Regulation of natural killer cell activity and interferon production in the rat lung following aerosol challenge. International Archives of Allergy and Applied Immunology, 78 (3), 318-325. doi: 10.1159/000233904

Preparation of interstitial lung cells by enzymatic digestion of tissue slices: preliminary characterization by morphology and performance in functional assays

Holt, P.G. , Degebrodt, A. , Venaille, T. , O'Leary, C. , Krska, K. , Flexman, J. , Farrell, H. , Shellam, G. , Young, P. , Penhale, J. , Robertson, T. and Papadimitriou, J.M. (1985). Preparation of interstitial lung cells by enzymatic digestion of tissue slices: preliminary characterization by morphology and performance in functional assays. Immunology, 54 (1), 139-147.

The Genetic Background Modulates the Effect of the Beige Gene on Susceptibility to Cytomegalovirus Infection in Mice

Shellam, G. R., Flexman, J. P., Farrell, H. E. and Papadimitriou, J. M. (1985). The Genetic Background Modulates the Effect of the Beige Gene on Susceptibility to Cytomegalovirus Infection in Mice. Scandinavian Journal of Immunology, 22 (2), 147-155. doi: 10.1111/j.1365-3083.1985.tb01867.x

Vaccination studies with a gH-deleted HSV-1 virus

McLean, C. S., Erturk, M., Ni Challanain, D., Jennings, R., Duncan, I. A., Bolt, S. L., Boursnell, M., Farrell, H., Minson, A. C. and Inglis, S. C. (1994). Vaccination studies with a gH-deleted HSV-1 virus. Publ by Inst of Chemical Engineers.