The University of Queensland

Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis

Ngougni Pokem, Perrin, Liu, Xin, Parker, Suzanne L, Verroken, Alexia, Collienne, Christine, Finet, Patrice, Wijnant, Gert-Jan, Laterre, Pierre-François, Roberts, Jason A, Van Bambeke, Françoise and Wittebole, Xavier (2023). Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis. Journal of Antimicrobial Chemotherapy, 79 (2), 429-442. doi: 10.1093/jac/dkad398

Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study

Novy, Emmanuel, Abdul-Aziz, Mohd H., Cheng, Vesa, Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Levkovich, Bianca J., McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Parker, Suzanne, Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2023). Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 68 (1) e0120123, e0120123. doi: 10.1128/aac.01201-23

Validating a novel three-times-weekly post-hemodialysis ceftriaxone regimen in infected Indigenous Australian patients—a population pharmacokinetic study

Tsai, Danny, Zam, Betty B., Tongs, Carleigh, Chiong, Fabian, Sajiv, Cherian, Pawar, Basant, Ashok, Aadith, Cooper, Brynley P, Tong, Steven Y C, Janson, Sonja, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2023). Validating a novel three-times-weekly post-hemodialysis ceftriaxone regimen in infected Indigenous Australian patients—a population pharmacokinetic study. Journal of Antimicrobial Chemotherapy, 78 (8), 1963-1973. doi: 10.1093/jac/dkad190

Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis

Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Garcia, Leandro Sousa, Souza Carvalho, Brenda Karoline, Costa, Amanda Araujo, Fachi, Mariana Millan, de Liz, Marcus Vinicius, de Souza, Alexandra Brito, Safe, Izabella Picinin, Pontarolo, Roberto, Wallis, Steven, Lipman, Jeffrey, Roberts, Jason A. and Cordeiro-Santos, Marcelo (2023). Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis. Tropical Medicine and Infectious Disease, 8 (6) 312, 1-10. doi: 10.3390/tropicalmed8060312

Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies

Hernández-Mitre, María Patricia, Won, Hayoung, Wallis, Steven C., Parker, Suzanne L. and Roberts, Jason A. (2023). Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies. Bioanalysis, 15 (12), 673-681. doi: 10.4155/bio-2023-0040

Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial

Keogh, Samantha, Dhanani, Jayesh, Levido, Annabel, Gracie, Chris, Ilushin, Vladislav, Palmer, Jennifer, Doubrovsky, Anna, Parker, Suzanne L., Pintara, Alexander, Huygens, Flavia and Coyer, Fiona (2023). Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial. Intensive and Critical Care Nursing, 75 103364, 1-8. doi: 10.1016/j.iccn.2022.103364

Serum creatinine and tacrolimus assessment with VAMS finger-prick microsampling: a diagnostic test study

Scuderi, Carla E., Parker, Suzanne L., Jacks, Margaret, John, George T., McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew J., Healy, Helen G., Roberts, Jason A. and Staatz, Christine E. (2023). Serum creatinine and tacrolimus assessment with VAMS finger-prick microsampling: a diagnostic test study. Kidney Medicine, 5 (4) 100610, 100610. doi: 10.1016/j.xkme.2023.100610

Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients

Adiraju, Santosh K. S., Sumi, Chandra D., Pandey, Saurabh, Cotta, Menino O., Roberts, Jason A, Lipman, Jeffrey, Wallis, Steven C. and Parker, Suzanne L. (2023). Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients. Bioanalysis, 15 (1), 31-42. doi: 10.4155/bio-2022-0230

Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients

Setiawan, Eko, Cotta, Menino Osbert, Abdul-Aziz, Mohd-Hafiz, Widjanarko, Doddy, Sosilya, Hernycane, Lukas, Dwi Lily, Wallis, Steven C., Parker, Suzanne and Roberts, Jason A. (2023). Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients. Clinical Pharmacokinetics, 62 (4), 1-14. doi: 10.1007/s40262-023-01219-5

Fingerprick microsampling methods can replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid, and prednisolone concentrations in adult kidney transplant patients

Scuderi, Carla, Parker, Suzanne, Jacks, Margaret, John, George T., McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Healy, Helen, Roberts, Jason and Staatz, Christine (2023). Fingerprick microsampling methods can replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid, and prednisolone concentrations in adult kidney transplant patients. Therapeutic Drug Monitoring, 45 (1), 69-78. doi: 10.1097/FTD.0000000000001024

Optimisation of treatments for oral Neisseria gonorrhoeae infection: Pharmacokinetics Study (STI-PK project) - study protocol for non-randomised clinical trial

Kong, Fabian Y. S., Unemo, Magnus, Lim, Shueh H., Latch, Ngaire, Williamson, Deborah A., Roberts, Jason A., Wallis, Steven C., Parker, Suzanne L., Landersdorfer, Cornelia B., Yap, Tami, Fairley, Christopher K., Chow, Eric P F, Lewis, David A., Hammoud, Mohamed A. and Hocking, Jane S. (2022). Optimisation of treatments for oral Neisseria gonorrhoeae infection: Pharmacokinetics Study (STI-PK project) - study protocol for non-randomised clinical trial. BMJ open, 12 (11) e064782, 1-8. doi: 10.1136/bmjopen-2022-064782

Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients

Ryan, Rochelle L., Jackson, Dwane, Hopkins, George, Eley, Victoria, Christensen, Rebecca, Van Zundert, Andre A. J., Wallis, Steven C., Lipman, Jeffrey, Parker, Suzanne L. and Roberts, Jason A. (2022). Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients. Antimicrobial Agents and Chemotherapy, 66 (7), e0041922. doi: 10.1128/aac.00419-22

Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2022). Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?. Journal of Antimicrobial Chemotherapy, 77 (8), 2227-2237. doi: 10.1093/jac/dkac168

Population pharmacokinetic model of piperacillin in critically ill patients and describing interethnic variation using external validation

Sanches, Cristina, Alves, Geisa C. S., Farkas, Andras, da Silva, Samuel Dutra, de Castro, Whocely Victor, Chequer, Farah Maria Drummond, Beraldi-Magalhães, Francisco, Magalhães, Igor Rafael dos Santos, Baldoni, André de Oliveira, Chatfield, Mark D., Lipman, Jeffrey, Roberts, Jason A. and Parker, Suzanne L. (2022). Population pharmacokinetic model of piperacillin in critically ill patients and describing interethnic variation using external validation. Antibiotics, 11 (4) 434, 434. doi: 10.3390/antibiotics11040434

Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study

Parker, Suzanne L., Irwin, Adam D., Hosking, Francine, August, Deanne, Schoenmaker, Brittany, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Davies, Mark W. (2022). Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study. International Journal of Antimicrobial Agents, 59 (2) 106513, 1-2. doi: 10.1016/j.ijantimicag.2021.106513

Evaluation of low-volume plasma sampling for the analysis of meropenem in clinical samples

Parker, Suzanne L., Wallis, Steven C., Fourie, Cheryl, Lassig-Smith, Melissa, Starr, Therese, Chikatamarla, Avinash, Dorofaeff, Tavey, Chatfield, Mark D., Lipman, Jeffrey and Roberts, Jason A. (2022). Evaluation of low-volume plasma sampling for the analysis of meropenem in clinical samples. Analytical and Bioanalytical Chemistry, 414 (6), 2155-2162. doi: 10.1007/s00216-021-03851-1

Perioperative cefazolin prophylaxis in pediatric cardiac surgery: a prospective, cohort study

Suna, Jessica, Moloney, Gregory, Marathe, Supreet P., Bierbach, Benjamin, Roberts, Jason A., Parker, Suzanne, Ungerer, Jacobus P.J., McWhinney, Brett, Dorofaeff, Tavey, Venugopal, Prem and Alphonso, Nelson (2022). Perioperative cefazolin prophylaxis in pediatric cardiac surgery: a prospective, cohort study. Annals of Thoracic Surgery, 114 (4), 1434-1440. doi: 10.1016/j.athoracsur.2022.02.047

Is dosing of ethambutol as part of a fixed-dose combination product optimal for mechanically ventilated ICU patients with tuberculosis? A population pharmacokinetic study

Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Sousa Garcia, Leandro, Souza Carvalho, Brenda Karoline, Fachi, Mariana Millan, de Liz, Marcus Vinicius, Pontarolo, Roberto, Lipman, Jeffrey, Cordeiro-Santos, Marcelo and Roberts, Jason A. (2021). Is dosing of ethambutol as part of a fixed-dose combination product optimal for mechanically ventilated ICU patients with tuberculosis? A population pharmacokinetic study. Antibiotics, 10 (12) 1559. doi: 10.3390/antibiotics10121559

The effect of haematocrit on measurement of the mid-infrared refractive index of plasma in whole blood

Rowe, David J., Owens, Daniel R., Parker, Suzanne L., Faust, Saul N., Wilkinson, James S. and Mashanovich, Goran Z. (2021). The effect of haematocrit on measurement of the mid-infrared refractive index of plasma in whole blood. Biosensors, 11 (11) 417. doi: 10.3390/bios11110417

Population pharmacokinetics of vancomycin and meropenem in pediatric extracorporeal membrane oxygenation support

Zylbersztajn, Brenda, Parker, Suzanne, Navea, Daniel, Izquierdo, Giannina, Ortiz, Paula, Torres, Juan Pablo, Fajardo, Cristian, Diaz, Rodrigo, Valverde, Cristian and Roberts, Jason (2021). Population pharmacokinetics of vancomycin and meropenem in pediatric extracorporeal membrane oxygenation support. Frontiers in Pharmacology, 12 709332, 1-10. doi: 10.3389/fphar.2021.709332

Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Roberts, Jason A., Lipman, Jeffrey, Coulthard, Mark G., Sparkes, Louise, Wallis, Steven C. and Parker, Suzanne L. (2021). Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children. Analytical and Bioanalytical Chemistry, 413 (17), 4483-4491. doi: 10.1007/s00216-021-03411-7

Microsampling to support pharmacokinetic clinical studies in pediatrics

Guerra Valero, Yarmarly, Dorofaeff, Tavey, Parker, Lisa, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2021). Microsampling to support pharmacokinetic clinical studies in pediatrics. Pediatric Research, 91 (6), 1-5. doi: 10.1038/s41390-021-01586-4

Population pharmacokinetics analysis of amikacin initial dosing regimen in elderly patients

Kato, Hideo, Parker, Suzanne L., Roberts, Jason A., Hagihara, Mao, Asai, Nobuhiro, Yamagishi, Yuka, Paterson, David L. and Mikamo, Hiroshige (2021). Population pharmacokinetics analysis of amikacin initial dosing regimen in elderly patients. Antibiotics, 10 (2) 100, 1-13. doi: 10.3390/antibiotics10020100

Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance

Sime, Fekade Bruck, Roberts, Jason A., Jeffree, Rosalind L., Pandey, Saurabh, Adiraju, Santosh, Livermore, Amelia, Butler, Jenie, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Cotta, Menino Osbert (2021). Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance. Clinical Pharmacokinetics, 60 (5), 655-664. doi: 10.1007/s40262-020-00979-8

Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain

Sime, Fekade B, Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain. Antimicrobial Agents and Chemotherapy, 65 (1) e01698-20, 1-11. doi: 10.1128/aac.01698-20

A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Stuart, Janine, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2020). A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies. Clinical Chemistry and Laboratory Medicine (CCLM), 59 (5), 921-933. doi: 10.1515/cclm-2020-1196

Determination of Levetiracetam in Plasma by a Modified HPLC-UV Method and Its Pharmacokinetic Application

Hernandez-Mitre, Maria P., Medellin-Garibay, Susanna E., Rodríguez-Leyva, Ildefonso, Rodríguez-Pinal, Cristian J., Zarazúa, Sergio, Jung-Cook, Helgi H., Parker, Suzanne L., Romano-Moreno, Silvia and del C. Milán-Segovia, Rosa (2020). Determination of Levetiracetam in Plasma by a Modified HPLC-UV Method and Its Pharmacokinetic Application. Mathews Journal of Pharmaceutical Science, 4 (1). doi: 10.30654/mjps.10004

The role of antibiotic pharmacokinetic studies performed post-licensing

Parker, Suzanne L., Abdul-Aziz, Mohd Hafiz and Roberts, Jason A. (2020). The role of antibiotic pharmacokinetic studies performed post-licensing. International Journal of Antimicrobial Agents, 56 (6) 106165, 106165. doi: 10.1016/j.ijantimicag.2020.106165

Antithrombin dosing guidelines in children underestimate dose needed for plasma level increase

Mattke, Adrian C., Johnson, Kerry E., Parker, Suzanne, Stocker, Christian, Gibbons, Kristen and Schibler, Andreas (2020). Antithrombin dosing guidelines in children underestimate dose needed for plasma level increase. Pediatric Critical Care Medicine, 21 (8), 746-752. doi: 10.1097/PCC.0000000000002383

Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture

Scuderi, Carla E., Parker, Suzanne L., Jacks, Margaret, John, George, McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Roberts, Jason A., Healy, Helen and Staatz, Christine E. (2020). Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture. Bioanalysis, 12 (13) bio-2020-0057, 873-881. doi: 10.4155/bio-2020-0057

Prophylactic cefazolin dosing in women with body mass index >35 kg·m−2 undergoing cesarean delivery : a pharmacokinetic study of plasma and interstitial fluid

Eley, Victoria A., Christensen, Rebecca, Ryan, Rochelle, Jackson, Dwane, Parker, Suzanne L., Smith, Matthew, van Zundert, Andre A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Prophylactic cefazolin dosing in women with body mass index >35 kg·m−2 undergoing cesarean delivery : a pharmacokinetic study of plasma and interstitial fluid. Anesthesia and Analgesia, 131 (1), 1-207. doi: 10.1213/ane.0000000000004766

The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Replacement Therapy Study

Roberts, Jason A., Joynt, Gavin M., Lee, Anna, Choi, Gordon, Bellomo, Rinaldo, Kanji, Salmaan, Mudaliar, M Yugan, Peake, Sandra L., Stephens, Dianne, Taccone, Fabio Silvio, Ulldemolins, Marta, Valkonen, Miia Maaria, Agbeve, Julius, Baptista, João P., Bekos, Vasileios, Boidin, Clement, Brinkmann, Alexander, Buizen, Luke, Castro, Pedro, Cole, C. Louise, Creteur, Jacques, De Waele, Jan J., Deans, Renae, Eastwood, Glenn M., Escobar, Leslie, Gomersall, Charles, Gresham, Rebecca, Jamal, Janattul Ain, Kluge, Stefan ... Young, Helen (2020). The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Replacement Therapy Study. Clinical Infectious Diseases, 72 (8), 1369-1378. doi: 10.1093/cid/ciaa224

A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 64 (1) e01655. doi: 10.1128/aac.01655-19

A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019). A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 411 (29), 7831-7840. doi: 10.1007/s00216-019-02184-4

Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study

Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019). Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, 58 (2), 274-284. doi: 10.1515/cclm-2019-0780

Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery

Gurunathan, Usha, Parker, Suzanne L., Maguire, Richard, Ramdath, Dale, Bijoor, Manu, Wallis, Steven C. and Roberts, Jason A. (2019). Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery. Anesthesia and Analgesia, 129 (3), 701-708. doi: 10.1213/ANE.0000000000003377

Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction. Antimicrobial Agents and Chemotherapy, 63 (10) e01265-19. doi: 10.1128/aac.01265-19

Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients

Sime, Fekade B., Byrn, Catherine J., Parker, Suzanne, Stuart, Janine, Butler, Jenie, Starr, Therese, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffery and Roberts, Jason A. (2019). Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients. Critical Care, 23 (1) 205, 205. doi: 10.1186/s13054-019-2483-9

Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study

Guerra Valero, Yarmarly C., Roberts, Jason A., Lipman, Jeffrey, Fourie, Cheryl, Starr, Therese, Wallis, Steven C. and Parker, Suzanne L. (2019). Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study. Journal of Pharmaceutical and Biomedical Analysis, 169, 288-292. doi: 10.1016/j.jpba.2019.03.018

Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model

Dhanani, Jayesh A., Diab, Sara, Chaudhary, Jivesh, Cohen, Jeremy, Parker, Suzanne L., Wallis, Steven C., Boidin, Clément, Barnett, Adrian, Chew, Michelle, Roberts, Jason A. and Fraser, John F. (2019). Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model. Anesthesiology, 131 (2), 1-355. doi: 10.1097/ALN.0000000000002752

Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?

Dimopoulos, George, Koulenti, Despoina, Parker, Suzanne L, Roberts, Jason A, Arvaniti, Kostoula and Poulakou, Garyphalia (2019). Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?. Expert Review of Anti-infective Therapy, 17 (3) 14787210.2019.1573669, 201-210. doi: 10.1080/14787210.2019.1573669

Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam

Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018). Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 (10) e01306, AAC.01306-18. doi: 10.1128/AAC.01306-18

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models

Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7

Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions

Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018). Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, 8 (6), 407-412. doi: 10.1016/j.jpha.2018.07.003

Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation

Dhanani, Jayesh A., Tang, Patrician, Wallis, Steven C., Parker, Suzanne L., Pandey, Preeti, Fraser, John F., Cohen, Jeremy, Barnett, Adrian, Roberts, Jason R. and Chan, Hak-Kim (2018). Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation. Pulmonary Pharmacology and Therapeutics, 50, 93-99. doi: 10.1016/j.pupt.2018.04.006

Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury

Parker, Suzanne L, Saxena, Manoj, Gowardman, John, Lipman, Jeffrey, Myburgh, John and Roberts, Jason A. (2018). Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. Journal of Critical Care, 47, 15-20. doi: 10.1016/j.jcrc.2018.05.016

Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review

Guerra Valero, Yarmarly C., Wallis, Steven C., Lipman, Jeffrey, Stove, Christophe, Roberts, Jason A. and Parker, Suzanne L. (2018). Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review. Bioanalysis, 10 (6), 407-423. doi: 10.4155/bio-2017-0269

A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent

Naicker, Saiyuri, Guerra Valero, Yarmarly C., Ordenez Meija, Jenny L., Lipman, Jeffrey, Roberts, Jason A., Wallis, Steven C. and Parker, Suzanne L. (2018). A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of Pharmaceutical and Biomedical Analysis, 148, 324-333. doi: 10.1016/j.jpba.2017.10.023

A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Weiss, Steven, Smith, Camilla, Russell, Lyndal, Smith, Paul, Roberts, Jason A and Wallis, Steven C (2017). A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples. Biomedical Chromatography, 31 (12) e4030, e4030. doi: 10.1002/bmc.4030

An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent

Parker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017). An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 (12), 911-924. doi: 10.4155/bio-2017-0019

Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin. Bioanalysis, 8 (21), 2235-2242. doi: 10.4155/bio-2016-0159

Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?

Dorofaeff, Tavey, Bandini, Rossella M., Lipman, Jeffrey, Ballot, Daynia E., Roberts, Jason A. and Parker, Suzanne L. (2016). Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?. Clinical Therapeutics, 38 (9), 1961-1975. doi: 10.1016/j.clinthera.2016.07.093

Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans

Parker, Suzanne L., Guerra Valero, Yarmarly C., Roberts, Darren M., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Biomedical Chromatography, 30 (6), 872-879. doi: 10.1002/bmc.3622

Is there a role for microsampling in antibiotic pharmacokinetic studies?

Parker, Suzanne L., Dorofaeff, Tavey, Lipman, Jeffrey, Ballot, Daynia E., Bandini, Rossella M., Wallis, Steven C. and Roberts, Jason A. (2016). Is there a role for microsampling in antibiotic pharmacokinetic studies?. Expert Opinion on Drug Metabolism and Toxicology, 12 (6), 601-614. doi: 10.1080/17425255.2016.1178238

The use and risks of antibiotics in critically ill patients

Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016). The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 (5), 667-678. doi: 10.1517/14740338.2016.1164690

A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans

Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015). A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115, 509-514. doi: 10.1016/j.jpba.2015.07.013

Population pharmacokinetics of fosfomycin in critically ill patients

Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015). Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (10), 6471-6476. doi: 10.1128/AAC.01321-15

Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling

Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015). Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 (19), 2585-2595. doi: 10.4155/bio.15.173

Optimizing dosing of antibiotics in critically ill patients

Parker, Suzanne L., Sime, Fekade B. and Roberts, Jason A. (2015). Optimizing dosing of antibiotics in critically ill patients. Current Opinion in Infectious Diseases, 28 (6), 497-504. doi: 10.1097/QCO.0000000000000206

An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine

Parker, Suzanne L., Adnan, Syamhanin, Meija, Jenny L. Ordonez, Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2015). An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine. Bioanalysis, 7 (18), 2311-2319. doi: 10.4155/bio.15.143

A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans

Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015). A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105, 39-45. doi: 10.1016/j.jpba.2014.11.042

What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review

Parker, Suzanne, Lipman, Jeffrey, Koulenti, Despoina, Dimopoulos, George and Roberts, Jason A. (2013). What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review. International Journal of Antimicrobial Agents, 42 (4), 289-293. doi: 10.1016/j.ijantimicag.2013.05.018

Steady-state dispositions of valproate and diflunisal alone and coadministered to healthy volunteers

Addison, RS, Parker-Scott, SL, Eadie, MJ, Hooper, WD and Dickinson, RG (2000). Steady-state dispositions of valproate and diflunisal alone and coadministered to healthy volunteers. European Journal of Clinical Pharmacology, 56 (9-10), 715-721. doi: 10.1007/s002280000211

Valproate metabolism during valproate-associated hepatotoxicity in a surviving adult patient

McLaughlin, DB, Eadie, MJ, Parker-Scott, SL, Addison, RS, Henderson, RD, Hooper, WD and Dickinson, RG (2000). Valproate metabolism during valproate-associated hepatotoxicity in a surviving adult patient. Epilepsy Research, 41 (3), 259-268. doi: 10.1016/S0920-1211(00)00151-0

Effect of naproxen co-administration on valproate disposition

Addison, RS, Parker-Scott, SL, Hooper, WD, Eadie, MJ and Dickinson, RG (2000). Effect of naproxen co-administration on valproate disposition. Biopharmaceutics & Drug Disposition, 21 (6), 235-242. doi: 10.1002/bdd.235

Improving tuberculosis treatment using mid-infrared spectroscopy for bedside therapeutic drug monitoring

Rowe, David J., Owens, Daniel R., Nedeljkovic, Milos, Stirling, Callum J., Cathie, Katrina, Parker, Suzanne L., Faust, Saul N., Mashanovich, Goran Z. and Wilkinson, James S. (2023). Improving tuberculosis treatment using mid-infrared spectroscopy for bedside therapeutic drug monitoring. Silicon Photonics XVIII 2023, San Francisco, CA United States, 30 January - 1 February 2023. Bellingham, WA United States: International Society for Optical Engineering. doi: 10.1117/12.2649135

Tacrolimus, mycophenolate and prednisolone concentration monitoring using microsampling instead of venepuncture in kidney transplant patients

Scuderi, C. E., Parker, S. L., Jacks, M., John, G. T., McWhinney, B., Ungerer, J., Mallett, A. J., Healy, H. G., Roberts, J. A. and Staatz, C. E. (2022). Tacrolimus, mycophenolate and prednisolone concentration monitoring using microsampling instead of venepuncture in kidney transplant patients. Society of Hospital Pharmacists of Australia, Brisbane, QLD, Australia, 1-3 December 2022.

Can microsampling methods replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid and prednisolone concentrations in adult kidney transplant patients?

Scuderi, Carla, Parker, Suzanne, Jacks, Margaret, John, George, McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Healy, Helen, Roberts, Jason and Staatz, Christine (2022). Can microsampling methods replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid and prednisolone concentrations in adult kidney transplant patients?. 57th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, NSW Australia, 17-19 October 2022. Richmond, VIC Australia: John Wiley & Sons.

Is creatine and tacrolimus measurement through VAMS microsampling the future for adult kidney transplant patients?

Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C. E. (2022). Is creatine and tacrolimus measurement through VAMS microsampling the future for adult kidney transplant patients? . Australian and New Zealand Society of Nephrology meeting, Sydney, NSW, Australia, October 2022.

Trimethoprim and sulphathiazole pharmacokinetic evaluation in adult kidney transplant recipients.

Scuderi, C., Jahan, S., Parker, S., Wallis, S., Jacks, M., John, G., McWhinney, B., Ungerer, J., Mallett. A., Healy, H., Roberts, J. and Staatz, C. (2022). Trimethoprim and sulphathiazole pharmacokinetic evaluation in adult kidney transplant recipients. . Society of Hospital Pharmacists of Australia conference, Adelaide, SA Australia, 24-26 February 2022. HOBOKEN: WILEY.

Evaluation of a closed loop blood sampling system in intensive care: A pilot randomised controlled trial. The enclose trial

Keogh, Samantha, Dhanani, Jayesh, Levido, Annabel, Gracie, Chris, Ilushin, Vladislav, Palmer, Jennifer, Parker, Suzanne, Doubrovsky, Anna, Hyugens, Flavia and Coyer, Fiona (2022). Evaluation of a closed loop blood sampling system in intensive care: A pilot randomised controlled trial. The enclose trial. ANZICS/ACCCN intensive care annual scientific meeting, Sydney, NSW Australia, 27-29 April 2022. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2022.08.015

Trimethoprim-sulfamethoxazole pharmacokinetic evaluation in adult kidney transplant patients

Scuderi, C.E., Jahan, S., Parker, S. L., Jacks, M., John, G., McWhinney, B., Ungerer, J., Mallett, A., Healy, H., Roberts, J.A. and Staatz, C. E. (2021). Trimethoprim-sulfamethoxazole pharmacokinetic evaluation in adult kidney transplant patients. Australian and New Zealand Society of Nephrology conference, Virtual, September 2021.

Interest in possible alternative methods to venepuncture-based monitoring in kidney transplant patients.

Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C.E. (2020). Interest in possible alternative methods to venepuncture-based monitoring in kidney transplant patients. . RBWH Symposium, Brisbane, QLD Australia, 7-11 December 2020.

The burden of venepuncture for kidney transplant patients and interest in possible solutions.

Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C.E. (2020). The burden of venepuncture for kidney transplant patients and interest in possible solutions. . Society of Hospital Pharmacists of Australia, Online, 21-22 November 2020.

Collaborations with Junior Colleagues for Building Research Capacity in the Public Sector

Siskind, D., Kisely, S. and Parker, S. (2017). Collaborations with Junior Colleagues for Building Research Capacity in the Public Sector. LONDON: SAGE PUBLICATIONS LTD. doi: 10.1177/0004867417702054

How to do qualitative research?

Parker, S. (2017). How to do qualitative research?. RANZCP 2017 Congress, Adelaide, Australia, 30 April - 4 May 2017. London, United Kingdom: Sage Publication.

Aspects of time- and concentration-related of valproate in humans

Addison, R. S., Dickinson, R. G., Eadie, M., Hooper, W. D., Parker-Scott, S. L. and Reith, D. (2000). Aspects of time- and concentration-related of valproate in humans. Annual Scientifc Meeting of ASCEPT, Newcastle, Australia, 03-06 Dec, 2000. Melbourne, Australia: Aust. Society of Clin. & Exp. Pharmacologists & Toxicologists.

Effect of naproxen co-administration on valproate disposition

Addison, R. S., Dickinson, R. G., Hooper, W. D. and Parker-Scott, S. L. (2000). Effect of naproxen co-administration on valproate disposition. DMW/ISSX 2000 Meeting, St Andrews, Scotland, 11-16 Jun, 2000. New York: Marcel Dekker.

Interplay between b-oxidation and glucuronidation of valproate in humans

Addison, R. S., Dickinson, R. G., Hooper, W. D. and Parker-Scott, S. L. (2000). Interplay between b-oxidation and glucuronidation of valproate in humans. DMW/ISSX 2000 Meeting, St Andrews, Scotland, 11-16 Jun, 2000. New York: Dekker.

The renal handling of valproate and several metabolites in humans

Addison, R. S., Dickinson, R. G., Eadie, M., Hooper, W. D. and Parker-Scott, S. L. (2000). The renal handling of valproate and several metabolites in humans. Annual Scientific Meeting of ASCEPT, Newcastle, Australia, 03-06 Dec, 2000. Melbourne: Aust Society of Clin. & Exp. Pharmacologists & Toxicologists.

Effect of Naproxen co-administration on Valproate disposition

Addison, R. S., Dickinson, R. G., Hooper, W. D. and Parker-Scott, S. L. (1999). Effect of Naproxen co-administration on Valproate disposition. 33rd Annual Scientific Meeting of ASCEPT, Sydney Convention & Exhibition Cen., Darling Harbour, 4 - 8 Dec, 1999. Sydney: Australian Society of Clinical & Experimental Pharmacology & Toxicology.

Steady state dispositions of Valproate and Diflunisal alone and coadministered to healthy volunteers

Addison, R. S., Dickinson, R. G., Eadie, M. J., Hooper, W. D. and Parker-Scott, S. L. (1999). Steady state dispositions of Valproate and Diflunisal alone and coadministered to healthy volunteers. ASCEPT, Sydney Convention & Exhibition Cen., Darling Harbour, 4 - 8 Dec, 1999. Sydney: Aust. Soc. of Clinical & Experimental Pharm. & Toxicol..

Translating innovative pharmacokinetic sampling techniques into improved antibiotic dosing regimens in critically ill patients

Parker, Suzanne (2016). Translating innovative pharmacokinetic sampling techniques into improved antibiotic dosing regimens in critically ill patients. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2016.70