Chinthaka Samaranayake is a Thoracic and Sleep physician and specialist in pulmonary vascular diseases, exercise physiology and thoracic malignancy. He graduated top of his class from The University of Auckland Medical School in 2011, and completed specialist physician training in Queensland, Australia. Dr Samaranayake has received extensive training in respiratory and sleep medicine, pulmonary vascular disease and interventions having worked at several Respiratory and Cardiology units across New Zealand, Australia and United Kingdom. After completing specialist training, he pursued post-graduate research fellowship for 2 years at Royal Brompton Hospital, London UK, working in the field of pulmonary hypertension and pulmonary embolism (2020-2022) whilst completing a PhD in experimetal and translational medicine which included conducting first-in-human clinical studies in three disease entities in collaboration with colleagues at Imperial College London. He subsequently worked as a Consultant Physician in Pulmonary Hypertension at Royal Brompton Hospital, before returning to Australia in 2023.
Dr Samaranayake’s research interests includes metabolic modulation of right ventricular function, invasive and non-invasive exercise physiology assessments, and early diagnosis and interventions in lung cancer. Dr Samaranayake has an established research track record in cardiopulmonary medicine, and his PhD research received a National Health and Medical Research Council (NHMRC) Postgraduate Scholarship. He has led several investigator-initiated clinical trials as chief investigator, including two randomised controlled trials. He has received numerous clinical and research awards for his work including a highly prestigious European Respiratory Society and APSR Young Investigator Award in 2022.
Dr Samaranayake currently works as a Consultant Thoracic Physician at The Prince Charles Hospital in Brisbane.
Journal Article: Pooled prevalence of depressive symptoms among medical students: an individual participant data meta-analysis
Pacheco, João Pedro Gonçalves, Bunevicius, Adomas, Oku, Afiong, Shindel, Alan, Torres, Albina Rodrigues, Bassols, Ana Margareth Siqueira, de Abreu Ramos-Cerqueira, Ana Teresa, Fernando, Antonio, Katkute, Arune, Mayda, Atilla Senih, Nair, Balakrishnan, Breyer, Benjamin N., Bakir, Bilal, Kelly, Brian, Angkurawaranon, Chaisiri, Sreeramareddy, Chandrashekhar, Samaranayake, Chinthaka, Saravanan, Coumaravelou, Del-Ben, Cristina Marta, Hinic, Darko, Goebert, Deborah, Ristic-Ignjatovic, Dragana, Al-faris, Eiad, Chang, Elaine, Venkatarao, Epari, Mojs, Ewa Helena, Youssef, Farid Fayez, Huang, Gan, Buneviciene, Inesa ... Tam, Wilson (2023). Pooled prevalence of depressive symptoms among medical students: an individual participant data meta-analysis. BMC Psychiatry, 23 (1) 251. doi: 10.1186/s12888-023-04745-5
Other Outputs: Advancing management of pulmonary thromboembolic disease: from acute pulmonary embolism to pulmonary hypertension
Samaranayake, Chinthaka (2023). Advancing management of pulmonary thromboembolic disease: from acute pulmonary embolism to pulmonary hypertension. PhD Thesis, Frazer Institute, The University of Queensland. doi: 10.14264/52b23f8
Conference Publication: Improved survival after treatment with pulmonary vasodilator therapies in patients with sarcoidosis-associated pulmonary hypertension: results from an international registry
Price, Laura, Kouranos, Vasilis, Baughman, Robert, Bloom, Chloe, Shlobin, Oksan, Nathan, Steven, Gupta, Rohit, Mccabe, Colm, Samaranayake, Chinthaka, Mason, Thomas, Renzoni, Elisabetta, Wells, Athol and Wort, John (2023). Improved survival after treatment with pulmonary vasodilator therapies in patients with sarcoidosis-associated pulmonary hypertension: results from an international registry. European Respiratory Society. doi: 10.1183/13993003.congress-2023.pa3488
Acute pulmonary embolism with comorbidities — how should i change my approach?
Samaranayake, Chinthaka B. and Wort, S. John (2023). Acute pulmonary embolism with comorbidities — how should i change my approach?. Emergent pulmonary embolism management in hospital practice. (pp. 101-111) edited by Colm McCabe and Aaron Waxman. Munich, Germany: World Scientific Publishing. doi: 10.1142/9781800612778_0008
Pacheco, João Pedro Gonçalves, Bunevicius, Adomas, Oku, Afiong, Shindel, Alan, Torres, Albina Rodrigues, Bassols, Ana Margareth Siqueira, de Abreu Ramos-Cerqueira, Ana Teresa, Fernando, Antonio, Katkute, Arune, Mayda, Atilla Senih, Nair, Balakrishnan, Breyer, Benjamin N., Bakir, Bilal, Kelly, Brian, Angkurawaranon, Chaisiri, Sreeramareddy, Chandrashekhar, Samaranayake, Chinthaka, Saravanan, Coumaravelou, Del-Ben, Cristina Marta, Hinic, Darko, Goebert, Deborah, Ristic-Ignjatovic, Dragana, Al-faris, Eiad, Chang, Elaine, Venkatarao, Epari, Mojs, Ewa Helena, Youssef, Farid Fayez, Huang, Gan, Buneviciene, Inesa ... Tam, Wilson (2023). Pooled prevalence of depressive symptoms among medical students: an individual participant data meta-analysis. BMC Psychiatry, 23 (1) 251. doi: 10.1186/s12888-023-04745-5
Samaranayake, Chinthaka Bhagya, Upham, John, Tran, Khoa, Howard, Luke S, Nguyen, Sean, Lwin, Myo, Anderson, James, Wahi, Sudhir, Price, Laura C, Wort, Stephen, Li, Wei, McCabe, Colm and Keir, Gregory J (2023). Right ventricular functional recovery assessment with stress echocardiography and cardiopulmonary exercise testing after pulmonary embolism: a pilot prospective multicentre study. BMJ Open Respiratory Research, 10 (1) e001637, e001637. doi: 10.1136/bmjresp-2023-001637
Samaranayake, Chinthaka B, Warren, Christopher, Rhamie, Serena, Haji, Gulam, Wort, S John, Price, Laura C, McCabe, Colm and Hull, James H (2023). Chaotic breathing in post COVID-19 breathlessness: a key feature of dysfunctional breathing can be characterized objectively by approximate entropy. ERJ Open Research, 9 (Immediate Access) 00117-2023, 00117-2023. doi: 10.1183/23120541.00117-2023
Samaranayake, Chinthaka B, Kempny, Aleksander, Naeije, Robert, Gatzoulis, Michael, Price, Laura C, Dimopoulos, Konstantinos, Zhao, Lan, Wort, Stephen J and McCabe, Colm (2023). Beta-blockade improves right ventricular diastolic function in exercising pulmonary arterial hypertension. European Respiratory Journal, 61 (5) 2300144, 1-4. doi: 10.1183/13993003.00144-2023
Dawes, Timothy J. W., McCabe, Colm, Dimopoulos, Konstantinos, Stewart, Iain, Bax, Simon, Harries, Carl, Samaranayake, Chinthaka B., Kempny, Aleksander, Molyneaux, Philip L., Seitler, Samuel, Semple, Thomas, Li, Wei, George, Peter M., Kouranos, Vasileios, Chua, Felix, Renzoni, Elisabetta A., Kokosi, Maria, Jenkins, Gisli, Wells, Athol U., Wort, Stephen J. and Price, Laura C. (2023). Phosphodiesterase 5 inhibitor treatment and survival in interstitial lung disease pulmonary hypertension: a Bayesian retrospective observational cohort study. Respirology, 28 (3), 262-272. doi: 10.1111/resp.14378
Samaranayake, Chinthaka B, Turnbull, Christopher, Neubauer, Stefan, Kylintireas, Ilias, Stradling, John, Craig, Sonya and McCabe, Colm (2023). Right ventricular responses to CPAP therapy in obstructive sleep apnoea: CMR analysis of the MOSAIC randomised trial. Pulmonary Circulation, 13 (1) e12201, 1-5. doi: 10.1002/pul2.12201
Ellender, Claire M., Samaranayake, Chinthaka, Reid, Natasha, Duce, Brett, Boyde, Mary, Winter, Sara and Hukins, Craig A. (2022). Randomized controlled trial on the efficacy of audio-visual health educational materials on CPAP adherence: the AHEAD trial. The Journal of Clinical Sleep Medicine, 18 (11), 2617-2625. doi: 10.5664/jcsm.10182
Samaranayake, Chinthaka B., Craigie, Michelle, Kempny, Aleksander, Bell, Peter T., McCann, Andrew, Wahi, Sudhir, Upham, John W., McCabe, Colm, Coucher, John and Keir, Gregory (2022). Right heart strain assessment on CTPA following acute pulmonary embolism: interobserver variability between expert radiologists and physicians. Respiratory Medicine, 200 106928, 1-7. doi: 10.1016/j.rmed.2022.106928
Use of sildenafil in patients with severe COVID-19 pneumonitis
McFadyen, Charles, Garfield, Ben, Mancio, Jennifer, Ridge, Carole A., Semple, Tom, Keeling, Archie, Ledot, Stephane, Patel, Brijesh, Samaranayake, Chinthaka B., McCabe, Colm, Wort, S John, Price, Susanna and Price, Laura C. (2022). Use of sildenafil in patients with severe COVID-19 pneumonitis. British Journal of Anaesthesia, 129 (1), e18-e21. doi: 10.1016/j.bja.2022.04.004
Samaranayake, Chinthaka B., McNiven, Ruth, Kempny, Aleksander, Harries, Carl, Price, Laura C., Gatzoulis, Michael, Dimopoulos, Konstantinos, Wort, Stephen J. and McCabe, Colm (2022). Exercise ventilatory reserve predicts survival in adult congenital heart disease associated pulmonary arterial hypertension with Eisenmenger physiology. International Journal of Cardiology Congenital Heart Disease, 7 100331, 100331. doi: 10.1016/j.ijcchd.2022.100331
Samaranayake, Chinthaka B., Anderson, James, McCabe, Colm, Zahir, Syeda Farah, Upham, John and Keir, Gregory (2022). Direct oral anticoagulants for cancer associated venous thromboembolisms: a systematic review and network meta-analysis: DOACs for VTE in Cancer. Internal Medicine Journal, 52 (2) 15049, 272-281. doi: 10.1111/imj.15049
Samaranayake, Chinthaka B., Warren, Christopher, Siewers, Karina, Craig, Stuart, Price, Laura C., Kempny, Aleksander, Dimopoulos, Konstantinos, Gatzoulis, Michael, Hopkinson, Nicholas S., Wort, Stephen J., Hull, James H. and McCabe, Colm (2021). Impact of cyanosis on ventilatory responses during stair climb exercise in Eisenmenger syndrome and idiopathic pulmonary arterial hypertension. International Journal of Cardiology, 341, 84-87. doi: 10.1016/j.ijcard.2021.08.020
Samaranayake, Chinthaka B., Keir, Gregory, Slader, Simon A. A., Tseng, T., Tran, Khoa, Anderson, James, McCann, Andrew, McCabe, Colm and Upham, John W. (2021). Use of direct oral anticoagulants for acute pulmonary embolisms in obesity: a propensity matched multicenter case-control study. ERJ Open Research, 7 (3) 00379-2021, 00379-2021. doi: 10.1183/23120541.00379-2021
Sarcoidosis associated pulmonary hypertension: an update
Samaranayake, Chinthaka B, McCabe, Colm, Wort, Stephen John and Price, Laura C (2021). Sarcoidosis associated pulmonary hypertension: an update. Current Opinion in Pulmonary Medicine, Publish Ahead of Print (5), 285-295. doi: 10.1097/MCP.0000000000000793
Bergbaum, Carmel, Samaranayake, Chinthaka B, Pitcher, Alex, Weingart, Emma, Semple, Thomas, Kokosi, Maria, Wells, Athol U, Montani, David, Dimopoulos, Konstantinos, McCabe, Colm, Kempny, Aleksander, Harries, Carl, Orchard, Elizabeth, Wort, S John and Price, Laura C (2021). A case series on the use of steroids and mycophenolate mofetil in idiopathic and heritable pulmonary veno-occlusive disease: is there a role for immunosuppression?. European Respiratory Journal, 57 (6) 2004354, 2004354. doi: 10.1183/13993003.04354-2020
Price, Laura C, Martinez, Guillermo, Brame, Aimee, Pickworth, Thomas, Samaranayake, Chinthaka, Alexander, David, Garfield, Benjamin, Aw, Tuan-Chen, McCabe, Colm, Mukherjee, Bhashkar, Harries, Carl, Kempny, Aleksander, Gatzoulis, Michael, Marino, Philip, Kiely, David G, Condliffe, Robin, Howard, Luke, Davies, Rachel, Coghlan, Gerry, Schreiber, Benjamin E, Lordan, James, Taboada, Dolores, Gaine, Sean, Johnson, Martin, Church, Colin, Kemp, Samuel V, Wong, Davina, Curry, Andrew, Levett, Denny ... Wort, Stephen John (2021). Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement. British Journal of Anaesthesia, 126 (4), 774-790. doi: 10.1016/j.bja.2021.01.005
Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control study
Samaranayake, Chinthaka B., Keir, Gregory, McCabe, Colm, Anderson, James, Tran, Khoa and Upham, John W. (2021). Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control study. ERJ Open Research, 7 (1) 00762, 1-4. doi: 10.1183/23120541.00762-2020
Samaranayake, Chinthaka B., Neill, Jane and Bint, Michael (2020). Respiratory acute discharge service: a hospital in the home programme for chronic obstructive pulmonary disease exacerbations (RADS study). Internal Medicine Journal, 50 (10), 1253-1258. doi: 10.1111/imj.14646
Samaranayake, Chinthaka B., Wright, Craig, Erigadoo, Shiv, Azzopardi, Maree, Putt, Michael and Bint, Michael (2020). A randomized controlled trial on optimal sampling sequence in radial guide sheath endobronchial ultrasound lung biopsy. Journal of Bronchology and Interventional Pulmonology, 27 (3), 205-211. doi: 10.1097/LBR.0000000000000651
Samaranayake, Chinthaka B., McCaffrey, Elizabeth, Coucher, John, Lehman, Margot, Mai, G. Tao and Murphy, Michelle A. (2020). Radiation therapy for augmenting the efficacy of immunotherapy in advanced non-small cell lung cancer: a case-controlled study. ERJ Open Research, 6 (1) 00189-2019, 00189-2019. doi: 10.1183/23120541.00189-2019
Right ventricular dysfunction and pulmonary hypertension following sub-massive pulmonary embolism
Samaranayake, Chinthaka B., Royle, Gordon, Jackson, Sharon and Yap, Elaine (2017). Right ventricular dysfunction and pulmonary hypertension following sub-massive pulmonary embolism. Clinical Respiratory Journal, 11 (6), 867-874. doi: 10.1111/crj.12429
Impact of ethnicity on outcomes after pulmonary embolism: an observational study in South Auckland
Samaranayake, Chinthaka B. and Yap, Elaine (2017). Impact of ethnicity on outcomes after pulmonary embolism: an observational study in South Auckland. New Zealand Medical Journal, 130 (1462), 109-111.
Evaluating the risk of sexually transmitted infections in mentally ill patients
Kenedi, Chris, Collier, Stephanie, Samaranayake, Chinthaka and Sapsford, Thomas (2017). Evaluating the risk of sexually transmitted infections in mentally ill patients. Current Psychiatry, 16 (1), 22-36.
The utility of a 'non-significant' coronary angiogram
Wang, T. K.M., Oh, T. H.T., Samaranayake, C. B., Webster, M. W.I., Stewart, J. T., Watson, T., Ellis, C. and Ruygrok, P. N. (2015). The utility of a 'non-significant' coronary angiogram. International Journal of Clinical Practice, 69 (12), 1465-1472. doi: 10.1111/ijcp.12723
Pseudoaneurysm of the radial artery following coronary angiography
Samaranayake, C. B., Timothy, T. J., Stewart, J. T. and Legget, M. E. (2015). Pseudoaneurysm of the radial artery following coronary angiography. Herz, 40 (4), 635-636. doi: 10.1007/s00059-013-3960-6
Samaranayake, Chinthaka B., Arroll, Bruce and Fernando, Antonio T. (2014). Sleep disorders, depression, anxiety and satisfaction with life among young adults: A survey of university students in Auckland, New Zealand. New Zealand Medical Journal, 127 (1399), 13-22.
Fatal quinine-induced thrombocytopenia from pulmonary haemorrhage
Samaranayake, C. B. and Yap, E. (2014). Fatal quinine-induced thrombocytopenia from pulmonary haemorrhage. Internal Medicine Journal, 44 (4), 423-425. doi: 10.1111/imj.12393
Giant complex aortic arch aneurysm and dissection
Samaranayake, Chinthaka B., Occleshaw, Christopher J., Nand, Parma and Legget, Malcolm E. (2013). Giant complex aortic arch aneurysm and dissection. Heart Lung and Circulation, 22 (10), 879-880. doi: 10.1016/j.hlc.2013.01.004
Return to work after heart transplantation: The New Zealand experience
Samaranayake, C. B., Ruygrok, P. N., Wasywich, C. A. and Coverdale, H. A. (2013). Return to work after heart transplantation: The New Zealand experience. Transplantation Proceedings, 45 (6), 2410-2413. doi: 10.1016/j.transproceed.2012.12.033
Management of psychogenic polydipsia and hyponatremia in an acute mental health unit
Samaranayake, Chinthaka B., Arora, Boris, Whiting, Jeremy and Kenedi, Christopher (2013). Management of psychogenic polydipsia and hyponatremia in an acute mental health unit. Australian and New Zealand Journal of Psychiatry, 47 (4), 395-396. doi: 10.1177/0004867412460595
Cancellations on the day of elective gynaecological surgery: The Counties Manukau experience
Wang, Tom K M, Samaranayake, Chinthaka B and Tout, Sarah (2013). Cancellations on the day of elective gynaecological surgery: The Counties Manukau experience. New Zealand Medical Journal, 126 (1374).
Sleep disorders among high school students in New Zealand
Fernando, Antonio T., Samaranayake, Chinthaka B., Blank, Christopher J., Roberts, Gareth and Arroll, Bruce (2013). Sleep disorders among high school students in New Zealand. Journal of Primary Health Care, 5 (4), 276-282. doi: 10.1071/hc13276
Prevalence of causes of insomnia in primary care: A cross-sectional study
Arroll, Bruce, Fernando III, Antonio, Falloon, Karen, Goodyear-Smith, Felicity, Samaranayake, Chinthaka and Warman, Guy (2012). Prevalence of causes of insomnia in primary care: A cross-sectional study. British Journal of General Practice, 62 (595), e99-e103. doi: 10.3399/bjgp12X625157
Satisfaction with life and depression among medical students in Auckland, New Zealand
Samaranayake, Chinthaka B and Fernando, Antonio T (2011). Satisfaction with life and depression among medical students in Auckland, New Zealand. New Zealand Medical Journal, 124 (1341).
Systematic review on ventral rectopexy for rectal prolapse and intussusception
Samaranayake, C. B., Luo, C., Plank, A. W., Merrie, A. E., Plank, L. D. and Bissett, I. P. (2010). Systematic review on ventral rectopexy for rectal prolapse and intussusception. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 12 (6), 504-512. doi: 10.1111/j.1463-1318.2009.01934.x
Luo, C., Samaranayake, C. B., Plank, L. D. and Bissett, I. P. (2010). Systematic review on the efficacy and safety of injectable bulking agents for passive faecal incontinence. Colorectal Disease, 12 (4), 296-303. doi: 10.1111/j.1463-1318.2009.01828.x
Outcome of combined melatonin and bright light treatments for delayed sleep phase disorder
Samaranayake, Chinthaka B., Fernando, Antonio and Warman, Guy (2010). Outcome of combined melatonin and bright light treatments for delayed sleep phase disorder. Australian and New Zealand Journal of Psychiatry, 44 (7), 676-676. doi: 10.3109/00048674.2010.482922
Price, Laura, Kouranos, Vasilis, Baughman, Robert, Bloom, Chloe, Shlobin, Oksan, Nathan, Steven, Gupta, Rohit, Mccabe, Colm, Samaranayake, Chinthaka, Mason, Thomas, Renzoni, Elisabetta, Wells, Athol and Wort, John (2023). Improved survival after treatment with pulmonary vasodilator therapies in patients with sarcoidosis-associated pulmonary hypertension: results from an international registry. European Respiratory Society. doi: 10.1183/13993003.congress-2023.pa3488
Use of pulmonary vasodilator therapy in anti-synthetase syndrome-associated pulmonary hypertension
Mason, Thomas, Samaranayake, Chinthaka, Mccabe, Colm, Dimopoulos, Kostas, Kouranos, Vasilis, Wort, John and Price, Laura (2023). Use of pulmonary vasodilator therapy in anti-synthetase syndrome-associated pulmonary hypertension. European Respiratory Society. doi: 10.1183/13993003.congress-2023.pa3495
Samaranayake, C, Niglas, M, Kempny, A, Baxan, N, Ashek, A, Pinguel, J, Dimopoulos, K, Price, L C, Wort, S J, Zhao, L and Mccabe, C (2022). Acute beat blockade improves right ventricular diastolic filling in pulmonary arterial hypertension: a rodent CMR and clinical human pressure-volume study. European Respiratory Society. doi: 10.1183/13993003.congress-2022.1844
Samaranayake, C, Kempny, A, Price, L C, Pinguel, J, Morris, E, Moriarty, E, Gummadi, M, Dimopoulos, K, Wort, S J, Zhao, L and Mccabe, C (2022). Metabolic modulation of the right ventricle and pulmonary circulation in pulmonary arterial hypertension: an interventional study using a Glucagon-like-peptide-1 (GLP-1) agonist. European Respiratory Society. doi: 10.1183/13993003.congress-2022.1210
Samaranayake, C., Craigie, M., Bell, P., Mccabe, C., Upham, J., Coucher, J. and Keir, G. (2022). Right heart strain assessment on CTPA following acute pulmonary embolism: interobserver variability between radiologists and thoracic physicians. 2022 ERS International Congress, Barcelona, Spain, 4-6 September 2022. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2022.1823
Samaranayake, C, Mcniven, R, Kempny, A, Price, L C, Harries, C, Gatzoulis, M, Dimopoulos, K, Wort, S J and Mccabe, C (2022). Ventilatory limitation during cardiopulmonary exercise testing predicts survival in patients with pulmonary arterial hypertension with Eisenmenger physiology. European Respiratory Society. doi: 10.1183/13993003.congress-2022.1809
Samaranayake, Chinthaka (2023). Advancing management of pulmonary thromboembolic disease: from acute pulmonary embolism to pulmonary hypertension. PhD Thesis, Frazer Institute, The University of Queensland. doi: 10.14264/52b23f8