The University of Queensland

Pharmacokinetic and pharmacodynamic tools to increase efficacy

Sinnollareddy, Mahipal G., Cotta, Menino O. and Roberts, Jason A. (2017). Pharmacokinetic and pharmacodynamic tools to increase efficacy. Antimicrobial stewardship. (pp. 85-98) edited by Celine Pulcini, Önder Ergönül, Füsun Can and Bojana Beović. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810477-4.00007-6

Pharmacokinetic and pharmacodynamic principles of antimicrobials

Osbert Cotta, Menino and Roberts, Jason (2016). Pharmacokinetic and pharmacodynamic principles of antimicrobials. Antimicrobial stewardship. (pp. 71-78) edited by Matthew Laundy, Mark Gilchrist and Laura Whitney. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780198758792.003.0009

Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

Chai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 1-9. doi: 10.1007/s00134-024-07353-3

Barriers and facilitators for the implementation and expansion of outpatient parenteral antimicrobial therapy: Systematic review

Mohammed, Solomon Ahmed, Cotta, Menino Osbert, Assefa, Getnet Mengistu, Erku, Daniel and Sime, Fekade (2024). Barriers and facilitators for the implementation and expansion of outpatient parenteral antimicrobial therapy: Systematic review. Journal of Hospital Infection, 147, 1-16. doi: 10.1016/j.jhin.2024.02.006

Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis

Harris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology spectrum, 12 (2) e0306523, e0306523. doi: 10.1128/spectrum.03065-23

Comment: Is off-label medication use in the ICU a problem?

Cotta, Menino O., Roberts, Jason A. and Reade, Michael C. (2023). Comment: Is off-label medication use in the ICU a problem?. Critical Care, 27 (1) 288, 288. doi: 10.1186/s13054-023-04546-y

Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study

Chai, Ming G., Roberts, Jason A., Kelly, Christina F., Ungerer, Jacobus P.J., McWhinney, Brett C., Lipman, Jeffrey, Farkas, Andras and Cotta, Menino O. (2023). Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study. Anaesthesia Critical Care and Pain Medicine, 42 (6) 101296, 101296. doi: 10.1016/j.accpm.2023.101296

Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis

Novy, Emmanuel, Roger, Claire, Roberts, Jason A. and Cotta, Menino Osbert (2023). Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis. Critical Care, 27 (1) 449, 1-17. doi: 10.1186/s13054-023-04742-w

In silico evaluation of a beta‐lactam dosing guideline among adults with serious infections

Williams, Paul, Cotta, Menino Osbert, Abdul‐Aziz, Mohd H., Wilks, Kathryn, Farkas, Andras and Roberts, Jason A. (2023). In silico evaluation of a beta‐lactam dosing guideline among adults with serious infections. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 43 (11), 1121-1130. doi: 10.1002/phar.2753

In silico evaluation of a vancomycin dosing guideline among adults with serious infections

Williams, Paul, Cotta, Menino Osbert, Abdul-Aziz, Mohd H., Wilks, Kathryn, Farkas, Andras and Roberts, Jason A (2023). In silico evaluation of a vancomycin dosing guideline among adults with serious infections. Therapeutic Drug Monitoring, 45 (5), 631-636. doi: 10.1097/FTD.0000000000001102

International survey of antibiotic dosing and monitoring in adult intensive care units

Williams, Paul G., Tabah, Alexis, Cotta, Menino Osbert, Sandaradura, Indy, Kanji, Salmaan, Scheetz, Marc H., Imani, Sahand, Elhadi, Muhammed, Luque-Pardos, Sònia, Schellack, Natalie, Sanches, Cristina, Timsit, Jean-Francois, Xie, Jiao, Farkas, Andras, Wilks, Kathryn, Roberts, Jason A., Brinkmann, Alexander, Ramanan, Mahesh, Koulenti, Despoina, Gurjar, Mohan, Sulaiman, Helmi, Shrestha, Gentle, Cortegiani, Andrea, Crespo, Monica, Ling, Lowell, Abidi, Khalid and Schellongowski, Peter (2023). International survey of antibiotic dosing and monitoring in adult intensive care units. Critical Care, 27 (1) 241, 1-11. doi: 10.1186/s13054-023-04527-1

A three-level model for therapeutic drug monitoring of antimicrobials at the site of infection

Brasier, Noé, Ates, H Ceren, Sempionatto, Juliane R., Cotta, Menino O., Widmer, Andreas F., Eckstein, Jens, Goldhahn, Jörg, Roberts, Jason A., Gao, Wei and Dincer, Can (2023). A three-level model for therapeutic drug monitoring of antimicrobials at the site of infection. The Lancet Infectious Diseases, 23 (10), e445-e453. doi: 10.1016/s1473-3099(23)00215-3

Ampicillin and ceftobiprole combination for the treatment of Enterococcus faecalis invasive infections: “The times they are a-changin”

Giuliano, Simone, Angelini, Jacopo, D’Elia, Denise, Geminiani, Monica, Barison, Roberto Daniele, Giacinta, Alessandro, Sartor, Assunta, Campanile, Floriana, Curcio, Francesco, Cotta, Menino Osbert, Roberts, Jason A., Baraldo, Massimo and Tascini, Carlo (2023). Ampicillin and ceftobiprole combination for the treatment of Enterococcus faecalis invasive infections: “The times they are a-changin”. Antibiotics, 12 (5) 879, 1-12. doi: 10.3390/antibiotics12050879

Beta-lactam dose optimisation in the intensive care unit: targets, therapeutic drug monitoring and toxicity

Legg, Amy, Carmichael, Sinead, Chai, Ming G., Roberts, Jason A. and Cotta, Menino O. (2023). Beta-lactam dose optimisation in the intensive care unit: targets, therapeutic drug monitoring and toxicity. Antibiotics, 12 (5) 870, 1-14. doi: 10.3390/antibiotics12050870

A systematic review on antimicrobial pharmacokinetic differences between Asian and non-Asian adult populations

Setiawan, Eko, Cotta, Menino Osbert, Roberts, Jason A. and Abdul-Aziz, Mohd Hafiz (2023). A systematic review on antimicrobial pharmacokinetic differences between Asian and non-Asian adult populations. Antibiotics, 12 (5) 803, 1-23. doi: 10.3390/antibiotics12050803

Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients

Adiraju, Santosh K. S., Sumi, Chandra D., Pandey, Saurabh, Cotta, Menino O., Roberts, Jason A, Lipman, Jeffrey, Wallis, Steven C. and Parker, Suzanne L. (2023). Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients. Bioanalysis, 15 (1), 31-42. doi: 10.4155/bio-2022-0230

Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]

Billot, Laurent, Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino Osbert, Davis, Joshua S., Finfer, Simon, Hammond, Naomi, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Roger, Claire, Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman and Dulhunty, Joel M. (2023). Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]. Critical Care and Resuscitation, 25 (1), 60-60. doi: 10.1016/j.ccrj.2023.04.012

Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients

Setiawan, Eko, Cotta, Menino Osbert, Abdul-Aziz, Mohd-Hafiz, Widjanarko, Doddy, Sosilya, Hernycane, Lukas, Dwi Lily, Wallis, Steven C., Parker, Suzanne and Roberts, Jason A. (2023). Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients. Clinical Pharmacokinetics, 62 (4), 1-14. doi: 10.1007/s40262-023-01219-5

Accuracy of a precision dosing software program for predicting antibiotic concentrations in critically ill patients

Chai, Ming G, Roberts, Jason A, Farkas, Andras and Cotta, Menino O (2023). Accuracy of a precision dosing software program for predicting antibiotic concentrations in critically ill patients. Journal of Antimicrobial Chemotherapy, 78 (2), 354-358. doi: 10.1093/jac/dkac392

Advancing precision-based antimicrobial dosing in critically ill patients

Cotta, Menino O., Lipman, Jeffrey and De Waele, Jan (2023). Advancing precision-based antimicrobial dosing in critically ill patients. Intensive Care Medicine, 49 (3), 324-326. doi: 10.1007/s00134-022-06969-7

Implementation of an antimicrobial stewardship program in the Australian private hospital system: qualitative study of attitudes to antimicrobial resistance and antimicrobial stewardship

Ayton, Darshini, Watson, Eliza, Betts, Juliana M., Doyle, Joseph, Teh, Benjamin, Valoppi, Glenn, Cotta, Menino, Robertson, Megan and Peel, Trisha (2022). Implementation of an antimicrobial stewardship program in the Australian private hospital system: qualitative study of attitudes to antimicrobial resistance and antimicrobial stewardship. BMC Health Services Research, 22 (1) 1554, 1-12. doi: 10.1186/s12913-022-08938-8

Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients

Truong, Anh Quan, Dao, Xuan Co, Vu, Dinh Hoa, Nguyen, Hoang Anh, Do, Thi Hong Gam, Tran, Nhan Thang, Tran, Nhat Minh, Vu, Ngan Binh, Pham, Hong Nhung, Bui, Van Cuong, Trinh, The Anh, Dang, Quoc Tuan, Nguyen, Gia Binh, Lipman, Jeffrey, Cotta, Menino O. and Roberts, Jason A. (2022). Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (11) e0032122, 1-11. doi: 10.1128/aac.00321-22

Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs

Jager, Nynke G. L., Chai, Ming G., van Hest, Reiner M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2022). Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs. Clinical Microbiology and Infection, 28 (9), 1211-1224. doi: 10.1016/j.cmi.2022.03.041

Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software

Roberts, Jason A., Bellomo, Rinaldo, Cotta, Menino O., Koch, Birgit C. P., Lyster, Haifa, Ostermann, Marlies, Roger, Claire, Shekar, Kiran, Watt, Kevin and Abdul-Aziz, Mohd H. (2022). Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software. Intensive Care Medicine, 48 (10), 1338-1351. doi: 10.1007/s00134-022-06847-2

Plasma and cerebrospinal fluid population pharmacokinetics of meropenem in neurocritical care patients: a prospective two-center study

Kumta, Nilesh, Heffernan, Aaron J., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wong, Wai Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2022). Plasma and cerebrospinal fluid population pharmacokinetics of meropenem in neurocritical care patients: a prospective two-center study. Antimicrobial Agents and Chemotherapy, 66 (8) e0014222, 1-12. doi: 10.1128/aac.00142-22

Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients

Setiawan, Eko, Abdul-Aziz, Mohd-Hafiz, Cotta, Menino Osbert, Susaniwati, Susaniwati, Cahjono, Heru, Sari, Ika Yunita, Wibowo, Tjipto, Marpaung, Ferdy Royland and Roberts, Jason A. (2022). Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients. Scientific Reports, 12 (1) 8930, 1-11. doi: 10.1038/s41598-022-12627-1

Hospital-based antimicrobial stewardship programs used in low- and middle-income countries: a scoping review

Setiawan, Eko, Abdul-Aziz, Mohd-Hafiz, Roberts, Jason A. and Cotta, Menino Osbert (2022). Hospital-based antimicrobial stewardship programs used in low- and middle-income countries: a scoping review. Microbial Drug Resistance, 28 (5), 566-584. doi: 10.1089/mdr.2021.0363

Indonesian healthcare providers' perceptions and attitude on antimicrobial resistance, prescription and stewardship programs

Setiawan, Eko, Cotta, Menino O., Abdul-Aziz, Mohd Hafiz, Sosilya, Hernycane, Widjanarko, Doddy, Wardhani, Dian K. and Roberts, Jason A. (2022). Indonesian healthcare providers' perceptions and attitude on antimicrobial resistance, prescription and stewardship programs. Future Microbiology, 17 (5), 363-375. doi: 10.2217/fmb-2021-0193

Therapeutic drug monitoring of antibiotics: defining the therapeutic range

Abdul–Aziz, Mohd H., Brady, Kara, Cotta, Menino Osbert and Roberts, Jason A. (2021). Therapeutic drug monitoring of antibiotics: defining the therapeutic range. Therapeutic Drug Monitoring, 44 (1), 19-31. doi: 10.1097/ftd.0000000000000940

Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis

Billot, Laurent, Lipman, Jeffrey, Brett, Stephen J., Waele, Jan J. De, Cotta, Menino Osbert, Davis, Joshua S., Finfer, Simon, Hammond, Naomi E., Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roger, Claire, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Dulhunty, Joel M. and For the BLING III Investigators (2021). Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis. Critical Care and Resuscitation, 23 (3), 273-284. doi: 10.51893/2021.3.oa4

Emerging therapeutic drug monitoring of anti‐infective agents in Australian hospitals: availability, performance and barriers to implementation

Sandaradura, Indy, Alffenaar, Jan‐Willem, Cotta, Menino O., Daveson, Kathryn, Day, Richard O., Van Hal, Sebastiaan, Lau, Cindy, Marriott, Deborah J. E., Penm, Jonathan, Roberts, Jason A., Tabah, Alexis, Williams, Paul and Imani, Sahand (2021). Emerging therapeutic drug monitoring of anti‐infective agents in Australian hospitals: availability, performance and barriers to implementation. British Journal of Clinical Pharmacology, 88 (2) bcp.14995, 669-679. doi: 10.1111/bcp.14995

Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations

Tu, Quyen, Cotta, Menino, Raman, Sainath, Graham, Nicolette, Schlapbach, Luregn and Roberts, Jason A (2021). Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations. Expert Review of Clinical Pharmacology, 14 (11), 1-17. doi: 10.1080/17512433.2021.1961578

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680

Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance

Sime, Fekade Bruck, Roberts, Jason A., Jeffree, Rosalind L., Pandey, Saurabh, Adiraju, Santosh, Livermore, Amelia, Butler, Jenie, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Cotta, Menino Osbert (2021). Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance. Clinical Pharmacokinetics, 60 (5), 655-664. doi: 10.1007/s40262-020-00979-8

A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey, Wong, Wai Tat, Joynt, Gavin M. and Cotta, Menino Osbert (2020). A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges. Antimicrobial Agents and Chemotherapy, 65 (1) e01998-20, 1-19. doi: 10.1128/aac.01998-20

Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices

Imani, Sahand, Alffenaar, Jan-Willem, Cotta, Menino O., Daveson, Kathryn, van Hal, Sebastiaan, Lau, Cindy, Marriott, Debbie, Penm, Jonathan, Roberts, Jason A., Tabah, Alexis, Trethewy, Nicholas, Williams, Paul and Sandaradura, Indy (2020). Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices. International Journal of Antimicrobial Agents, 56 (6) 106180, 106180. doi: 10.1016/j.ijantimicag.2020.106180

What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?

Cotta, Menino Osbert, Abdul-Aziz, Mohd Hafiz, Frey, Otto R., Sime, Fekade Bruck, Roberts, Jason A. and Roehr, Anka C. (2020). What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?. Therapeutic Drug Monitoring, 42 (4), 626-630. doi: 10.1097/ftd.0000000000000731

What are the current approaches to optimising antimicrobial dosing in the intensive care unit?

Chai, Ming G., Cotta, Menino O., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). What are the current approaches to optimising antimicrobial dosing in the intensive care unit?. Pharmaceutics, 12 (7) 638, 1-22. doi: 10.3390/pharmaceutics12070638

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

De Bus, Liesbet, Depuydt, Pieter, Steen, Johan, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, Akova, Murat, Cotta, Menino Osbert, De Pascale, Gennaro, Dimopoulos, George, Fujitani, Shigeki, Garnacho-Montero, Jose, Leone, Marc, Lipman, Jeffrey, Ostermann, Marlies, Paiva, José-Artur, Schouten, Jeroen, Sjövall, Fredrik, Timsit, Jean-François, Roberts, Jason A., Zahar, Jean-Ralph, Zand, Farid, Zirpe, Kapil, De Waele, Jan J. and DIANA study group (2020). Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive Care Medicine, 46 (7), 1404-1417. doi: 10.1007/s00134-020-06111-5

Modifiable risk factors for multidrug-resistant Gram-negative infection in critically ill burn patients: a systematic review and meta-analysis

Vickers, Mark L., Malacova, Eva, Milinovich, Gabriel J., Harris, Patrick, Eriksson, Lars, Dulhunty, Joel M. and Cotta, Menino O. (2019). Modifiable risk factors for multidrug-resistant Gram-negative infection in critically ill burn patients: a systematic review and meta-analysis. ANZ Journal of Surgery, 89 (10) ans.15393, 1256-1260. doi: 10.1111/ans.15393

Implementasi Antimicrobial Stewardship Program di Kawasan Asia: Sebuah Kajian Sistematis

Setiawan, Eko, Wibowo, Yosi I., Setiadi, Adji P., Nurpatria, Yul'aini, Sosilya, Hernycane, Wardhani, Dian K., Cotta, Menino O., Abdul-Aziz, Mohd-Hafiz and Roberts, Jason (2019). Implementasi Antimicrobial Stewardship Program di Kawasan Asia: Sebuah Kajian Sistematis. Indonesian Journal of Clinical Pharmacy, 8 (2), 141-156. doi: 10.15416/ijcp.2019.8.2.141

Dexmedetomidine prescribing in Australian intensive care units: an observational study

O'Brien, Daniel W., Cotta, Menino O., Choo, Lyn, Fowler, Stephen, Downey, Maria, Fisquet, Stephanie, Tan, Ivy and Roberts, Jason A. (2019). Dexmedetomidine prescribing in Australian intensive care units: an observational study. Journal of Pharmacy Practice and Research, 49 (5) jppr.1529, 477-481. doi: 10.1002/jppr.1529

Antibiotic exposure at the site of infection: principles and assessment of tissue penetration

Jager, Nynke G. L., van Hest, Reinier M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2019). Antibiotic exposure at the site of infection: principles and assessment of tissue penetration. Expert Review of Clinical Pharmacology, 12 (7), 623-634. doi: 10.1080/17512433.2019.1621161

Narrative study on pharmacokinetics of antibiotics among critically ill patients: the implication on the pharmacokinetics-pharmacodynamics target attainment

Setiawan, Eko, Widyati, Marpaung, Ferdy Royland, Sukandar, Edy, Susaniwati, Lukas, Dwi Lily, Wijono, Heru, Warindra, Taufin, Kurniawan, Roni, Wibowo, Tjipto, Hendradi, Wahyu, Cotta, Menino Osbert, Abdul-Aziz, Mohd-Hafiz and Roberts, Jason (2019). Narrative study on pharmacokinetics of antibiotics among critically ill patients: the implication on the pharmacokinetics-pharmacodynamics target attainment. Pharmaceutical Sciences and Research, 6 (1). doi: 10.7454/psr.v6i1.4274

A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III

Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Glass, Parisa, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Billot, Laurent and Dulhunty, Joel M. (2019). A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III. Critical Care and Resuscitation, 21 (1), 63-68. doi: 10.1016/s1441-2772(23)00582-3

Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram

Williams, Paul, Beall, Gareth, Cotta, Menino Osbert and Roberts, Jason A. (2019). Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram. International Journal of Antimicrobial Agents, 55 (2) 105837, 105837. doi: 10.1016/j.ijantimicag.2019.10.018

Diagnostic and medical needs for therapeutic drug monitoring of antibiotics

Mabilat, Claude, Gros, Marie Francoise, Nicolau, David, Mouton, Johan W., Textoris, Julien, Roberts, Jason A., Cotta, Menino O., van Belkum, Alex and Caniaux, Isabelle (2019). Diagnostic and medical needs for therapeutic drug monitoring of antibiotics. European Journal of Clinical Microbiology and Infectious Diseases, 39 (5), 791-797. doi: 10.1007/s10096-019-03769-8

Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unit

Williams, Paul, Cotta, Menino Osbert and Roberts, Jason A. (2019). Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unit. Seminars in Respiratory and Critical Care Medicine, 40 (4), 476-487. doi: 10.1055/s-0039-1693498

Risk factors for multidrug-resistant Gram-negative infection in burn patients

Vickers, Mark L., Dulhunty, Joel M., Ballard, Emma, Chapman, Paul, Muller, Michael, Roberts, Jason A. and Cotta, Menino O. (2018). Risk factors for multidrug-resistant Gram-negative infection in burn patients. ANZ Journal of Surgery, 88 (5), 480-485. doi: 10.1111/ans.14144

Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey and Cotta, Menino Osbert (2017). Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?. Clinical Pharmacokinetics, 57 (4), 439-454. doi: 10.1007/s40262-017-0588-3

Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients

Roger, Claire, Cotta, Menino O., Muller, Laurent, Wallis, Steven C., Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2017). Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 50 (2), 227-231. doi: 10.1016/j.ijantimicag.2017.03.018

What are the similarities and differences in antimicrobial prescribing between Australian public and private hospitals?

Cotta, M. O., Chen, C., Tacey, M., James, R. S., Buising, K. L., Marshall, C. and Thursky, K. A. (2016). What are the similarities and differences in antimicrobial prescribing between Australian public and private hospitals?. Internal Medicine Journal, 46 (10), 1182-1188. doi: 10.1111/imj.13209

Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials

Roberts, Jason A., Abdul-Aziz, Mohd-Hafiz, Davis, Joshua S., Dulhunty, Joel M., Cotta, Menino O., Myburgh, John, Bellomo, Rinaldo and Lipman, Jeffrey (2016). Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials. American Journal of Respiratory and Critical Care Medicine, 194 (6), 681-691. doi: 10.1164/rccm.201601-0024OC

Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?

Mcdonald, Craig, Cotta, Menino O., Little, Peter J., Mcwhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2016). Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?. Minerva Anestesiologica, 82 (9), 957-965.

Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists

Cotta, Menino O., Dulhunty, Joel M., Roberts, Jason A., Myburgh, John and Lipman, Jeffrey (2016). Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists. International Journal of Antimicrobial Agents, 47 (6), 436-438. doi: 10.1016/j.ijantimicag.2016.02.017

We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?

Cotta, Menino Osbert, Roberts, Jason A. and Lipman, Jeffrey (2016). We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?. Critical Care, 20 (1) 163. doi: 10.1186/s13054-016-1348-8

Evaluating antimicrobial therapy: how reliable are remote assessors?

Cotta, Menino Osbert, Spelman, Tim, Chen, Caroline, James, Rodney S., Liew, Danny, Thursky, Karin A., Buising, Kirsty L. and Marshall, Caroline (2016). Evaluating antimicrobial therapy: how reliable are remote assessors?. Infection, Disease & Health, 21 (1), 3-10. doi: 10.1016/j.idh.2016.01.002

A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit

Tabah, Alexis, Cotta, Menino Osbert, Garnacho-Montero, Jose, Schouten, Jeroen, Roberts, Jason A., Lipman, Jeffrey, Tacey, Mark, Timsit, Jean-Francois, Leone, Marc, Zahar, Jean Ralph and De Waele, Jan J. (2016). A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit. Clinical Infectious Diseases, 62 (8), 1009-1017. doi: 10.1093/cid/civ1199

The use and risks of antibiotics in critically ill patients

Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016). The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 (5), 667-678. doi: 10.1517/14740338.2016.1164690

Does critical illness change levofloxacin pharmacokinetics?

Roberts, Jason A., Cotta, Menino Osbert, Cojutti, Piergiorgio, Lugano, Manuela, Rocca, Giorgio D. and Pea, Federico (2016). Does critical illness change levofloxacin pharmacokinetics?. Antimicrobial Agents and Chemotherapy, 60 (3), 1459-1463. doi: 10.1128/AAC.02610-15

Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos

Cotta, M. O., Roberts, J. A. and Lipman, J. (2015). Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos. Medicina Intensiva (English Edition), 39 (9), 563-572. doi: 10.1016/j.medine.2015.07.001

Antimicrobial stewardship in Australian hospitals and other settings

Cairns, Kelly A., Roberts, Jason A., Cotta, Menino O. and Cheng, Allen C. (2015). Antimicrobial stewardship in Australian hospitals and other settings. Infectious Diseases and Therapy, 4 (Supp.1), 27-38. doi: 10.1007/s40121-015-0083-9

The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs

Tabah, Alexis, De Waele, Jan, Lipman, Jeffrey, Zahar, Jean Ralph, Cotta, Menino Osbert, Barton, Greg, Timsit, Jean-Francois and Roberts, Jason A. (2015). The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs. Journal of Antimicrobial Chemotherapy, 70 (9), 2671-2677. doi: 10.1093/jac/dkv165

Measuring antimicrobial prescribing quality in Australian hospitals: development and evaluation of a national antimicrobial prescribing survey tool

James, Rodney, Upjohn, Lydia, Cotta, Menino, Luu, Susan, Marshall, Caroline, Buising, Kirsty and Thursky, Karin (2015). Measuring antimicrobial prescribing quality in Australian hospitals: development and evaluation of a national antimicrobial prescribing survey tool. Journal of Antimicrobial Chemotherapy, 70 (6) dkv047, 1912-1918. doi: 10.1093/jac/dkv047

Post-operative iatrogenic pneumothorax and associated mortality: lessons learnt

Cotta, Menino Osbert, Tan, Shu Yi, Cotta, Maria Virginia Pereira E. and Bowers, Kaye (2015). Post-operative iatrogenic pneumothorax and associated mortality: lessons learnt. ANZ Journal of Surgery, 85 (5), 389-390. doi: 10.1111/ans.12955

Implementing antimicrobial stewardship in the Australian private hospital system: a qualitative study

Cotta, Menino O., Robertson, Megan S., Marshall, Caroline, Thursky, Karin A., Liew, Danny and Buising, Kirsty L. (2015). Implementing antimicrobial stewardship in the Australian private hospital system: a qualitative study. Australian Health Review, 39 (3), 315-322. doi: 10.1071/AH14111

Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring

Cotta, Menino Osbert, Gowen, Belinda, Truloff, Natasha, Bursle, Evan, Mcwhinney, Brett, Ungerer, Jacobus P. J., Roberts, Jason A. and Lipman, Jeffrey (2015). Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring. Infectious Diseases, 47 (10), 739-742. doi: 10.3109/23744235.2015.1021831

An experience with dracunculiasis in Melbourne, Australia

Cotta, Menino O., Cotta, Maria V. Pereira E., Darby, Jonathan, Sutherland, Tom R. and Sheorey, Harsha (2014). An experience with dracunculiasis in Melbourne, Australia. Pathology, 46 (7), 652-653. doi: 10.1097/PAT.0000000000000169

Attitudes towards antimicrobial stewardship: results from a large private hospital in Australia

Cotta, Menino O., Robertson, Megan S., Tacey, Mark, Marshall, Caroline, Thursky, Karin A., Liew, Danny and Buising, Kirsty L. (2014). Attitudes towards antimicrobial stewardship: results from a large private hospital in Australia. Healthcare Infection, 19 (3), 89-94. doi: 10.1071/HI14008

Using periodic point-prevalence surveys to assess appropriateness of antimicrobial prescribing in Australian private hospitals

Cotta, M. O., Robertson, M. S., Upjohn, L. M., Marshall, C., Liew, D. and Buising, K. L. (2014). Using periodic point-prevalence surveys to assess appropriateness of antimicrobial prescribing in Australian private hospitals. Internal Medicine Journal, 44 (3), 240-246. doi: 10.1111/imj.12353

Antimicrobial stewardship of β-lactams in intensive care units

Cotta, Menino Osbert, Roberts, Jason A., Tabah, Alexis, Lipman, Jeffrey, Vogelaers, Dirk and Blot, Stijn (2014). Antimicrobial stewardship of β-lactams in intensive care units. Expert Review of Anti-Infective Therapy, 12 (5), 581-595. doi: 10.1586/14787210.2014.902308

Antimicrobial stewardship in Victorian hospitals: a statewide survey to identify current gaps

James, Rodney S., McIntosh, Kylle A., Luu, Susan B., Cotta, Menino O., Marshall, Caroline, Thursky, Karin A. and Buising, Kirsty L. (2013). Antimicrobial stewardship in Victorian hospitals: a statewide survey to identify current gaps. Medical Journal of Australia, 199 (10), 692-695. doi: 10.5694/mja13.10422

Development of an electronic case record form (AU-Crit) for antimicrobial stewardship program initiation

Pathiraj, John Preshanth Kumar, Hande, Manjunatha H., Varma, Murulidhar, Mukhyopadhay, Chiranjoy, Jathanna, Roshan David, Cotta (Os), Menino Osbert and Ghaffur, Abdul (2016). Development of an electronic case record form (AU-Crit) for antimicrobial stewardship program initiation. 5th International Australasian College for Infection Prevention and Control 2016, Melbourne, VIC, Australia, 20-23 November 2016. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.idh.2016.09.039

The ADMIN-ICU survey: A survey on antimicrobials dosing and monitoring strategies in intensive care units

Tabah, A., Roberts, J., De Waele, J. J., Lipman, J., Zahar, J. R., Cotta, M. O., Barton, G. and Timsit, J. -F. (2014). The ADMIN-ICU survey: A survey on antimicrobials dosing and monitoring strategies in intensive care units. 27th Annual Congress of the European Society of Intensive Care Medicine (ESICM), Barcelona, Spain, 27 September-1 October 2014. Heidelberg, Germany: Springer. doi: 10.1007/s00134-014-3451-0