Pore Engineering of Chromatography Membranes for Bioseparation (2023–2026)
Abstract:
Protein separation and purification is an essential unit operation in manufacturing processes of therapeutic
proteins. The project aims to advance the practical applications of chromatography membrane, an emerging
technology for protein separation and purification, by tailoring membrane pore geometry and surface functionality
to achieve enhanced separation performance. The project expects to generate advanced knowledge and
techniques in the fields of reactive polymer synthesis, functional membrane fabrication and application in
bioseparation. The innovative membranes developed in the project are able to improve the production capacity of
therapeutic protein manufacturing processes, providing significant economic benefits to Australia.