A next-generation whole parasite bovine Babesia vaccine (ARC Discovery Project administered by Griffith University) (2023–2025)
Abstract:
In Australia, Babesia parasites cause most of the severe and often fatal cases of cattle-tick fever, a globally
significant tick-borne disease. It can be prevented by a live-attenuated parasite vaccine which has critical
limitations of a 4-day shelf-life and risk of severe disease if administered to adult cattle. This project aims to
evaluate in cattle a novel whole parasite Babesia bovis vaccine that cannot cause disease and can be preserved
as an off-the-shelf product without losing efficacy. The expected outcome is a significantly improved vaccine for a
major infectious disease that affects primary food production. As the disease imposes a major economic burden, it
will have great benefit for the Australian livestock industry.