Cell fluid interaction: inside and outside cells (2023–2026)

Abstract:
The project aims to measure mechanics at the cellular level using a combination of optical tweezers for measurement of nano-scale environment around/inside cells and light-sheet microscopy for imaging. The project expects to generate new knowledge about movement of cells through their environment, relating to collective behaviour which is of importance in understanding infections and formation of biofilms. Expected outcomes include deepened understanding of an enigmatic process conserved from amoebae to humans, by which cells `drink and eat by `gulping fluid and supplement their nutrient intake by degrading proteins and cell debris. It will generate new knowledge of these processes to better understand how mechanics affects cellular life.
Grant type:
ARC Discovery Projects
Researchers:
  • Professor
    School of Mathematics and Physics
    Faculty of Science
    Professor
    School of Mathematics and Physics
    Faculty of Science
    Affiliate of ARC COE in Quantum Bio
    ARC Centre of Excellence in Quantum Biotechnology
    Faculty of Science
    Affiliate of ARC COE for Engineered
    ARC Centre of Excellence for Engineered Quantum Systems
    Faculty of Science
    Affiliate Professor
    Australian Institute for Bioengineering and Nanotechnology
  • Senior Lecturer
    School of Mathematics and Physics
    Faculty of Science
    Senior Lecturer
    School of Mathematics and Physics
    Faculty of Science
  • NHMRC Leadership Fellow
    Institute for Molecular Bioscience
    NHMRC Leadership Fellow
    Institute for Molecular Bioscience
    Affiliate of ARC COE in Quantum Bio
    ARC Centre of Excellence in Quantum Biotechnology
    Faculty of Science
  • Research Fellow
    School of Mathematics and Physics
    Faculty of Science
    Research Fellow
    School of Mathematics and Physics
    Faculty of Science
    Affiliate of ARC COE for Engineered
    ARC Centre of Excellence for Engineered Quantum Systems
    Faculty of Science
Funded by:
Australian Research Council