Untangling the matrix of bacterial biofilms (2023–2026)

This research aims to use forefront molecular microbiology and biophysical approaches to advance fundamental knowledge on bacterial biofilms. These bacterial clusters are held together by an extracellular matrix comprised of bacterial-derived fibrous protein and the polysaccharide cellulose, which imparts structural integrity and resistance to antimicrobials. The major goals of this project are to dissect how bacteria regulate production of the biofilm matrix, and examine how changes in the composition of the matrix alters its properties, including the penetration of antimicrobial peptides and antibiotics. The outcomes will help address the economic burden of difficult to treat industrial, environmental and biomedical biofilms.
Grant type:
ARC Discovery Projects
  • Professorial Research Fellow & Grou
    Institute for Molecular Bioscience
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council