A cyclic ion-mobility mass spectrometer for resolving molecular isomers (ARC LIEF application led by Queensland University of Technology) (2022)
Abstract:
Both our fundamental understanding of the natural world and our ability to shape new functional materials
depends on our ability to assign molecular structure. Rapid assignment of molecular structures within complex
biological or synthetic mixtures and, particularly, the differentiation between closely related structures (i.e.,
isomers) is a frontier challenge for chemists and biologists alike. The requested infrastructure directly addresses
this challenge by making next-generation (cyclic) ion-mobility mass spectrometry available to Australian
researchers for the first time. This new capability will drive biomolecular discovery across both plant and animal
kingdoms, and accelerate advances in materials science.