Engineering Tissue Organisation Using Intelligent Additive Biomanufacturing (2022–2025)
Abstract:
This project aims to organize and shape the formation of lab-grown tissue by 3D printing structures which control
the behaviour of cells. This cell behaviour control will be accomplished through an interdisciplinary and multiscale
pipeline of additive micromanufacturing, bioreactor engineering, cell culture, single-cell imaging, and
computational modelling. In contrast with current empirical approaches, this quantitative and predictive
understanding of how to control biological processes within 3D printed environments will design and engineer
more robust, customisable, scalable, and economical cell culture platforms able to optimally manufacture bespoke
and complex 3D tissues for future agricultural, pharmaceutical, or medical products.