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Making peptides orally bioavailable (2022–2025)

Abstract:
Bioactive peptides are exceptionally useful molecules, however to fully realise their exciting applications key limitations need to be overcome: they can't be delivered orally and they do not last long in the body. This project aims to develop a molecular tag that can dramatically enhance both the oral absorption and time in the body of a peptide. This will include identifying the key elements of the tag required for function, the breadth of peptide cargoes it can be applied to and the mechanisms underlying this technology. The outcomes of this project will facilitate the future development of peptides for biotechnology, pharmaceutical and veterinary applications.
Grant type:
ARC Discovery Projects
Researchers:

  • Associate Professor Richard Clark

    Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Affiliate Associate Professor of In
    Institute for Molecular Bioscience

  • Professor Trent Woodruff

    NHMRC Professorial Fellow
    School of Biomedical Sciences
    Faculty of Medicine
    Affiliate Professor of Queensland B
    Queensland Brain Institute

  • Associate Professor Johan Rosengren

    Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
Australian Research Council