Methods for protein structure analysis by electron paramagnetic resonance (ARC Discovery Project administered by The Australian National University) (2021–2024)
Abstract:
This highly interdisciplinary project aims to establish new tools to analyse the structure and motions of proteins
that are otherwise difficult to study. A combination of advanced biochemistry, modern magnetic spectroscopy
methods, and high-performance computing techniques will be applied to study proteins at physiological
concentrations and in complex environments. New techniques will be developed and tested on proteins of high
biochemical or biomedical importance, and the approach will be applied to established drug targets.