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Viral and host RNA methylation in mosquitoes (2021–2024)

Abstract:
Mosquitoes transmit a variety of viruses to humans and animals through blood feeding. This project aims to investigate one of the most common modifications of RNA molecules, known as N6-methyladenosine (m6A), in an important mosquito vector, Aedes aegypti, and its alterations upon infection with pathogenic as well as mosquito-specific viruses. In addition, m6A modification of viral genomic RNA and its importance in virus replication will be investigated. Expected outcomes of this project include fundamental understanding of RNA methylation in mosquitoes and their role in mosquito biology and virus replication.
Grant type:
ARC Discovery Projects
Researchers:

  • Professor Sassan Asgari

    Professor
    School of the Environment
    Faculty of Science
    Professor
    School of the Environment
    Faculty of Science
    of School of Chemistry and Molecula
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council