Gain from pain: new tools from venomous animals for exploring pain pathways (2019–2022)

Abstract:
Many venomous animals use their venom defensively and envenomation is frequently associated with rapid and often excruciating pain. In most cases, the molecular mechanisms by which they achieve this is unknown. This Discovery Project will use a diverse array of biochemical, pharmacological, and biophysical techniques to explore animal venoms for new pain-causing toxins to determine their structure and mechanism of action. The research is likely to uncover toxins that employ new mechanisms of pain signalling, leading to new insights into pain physiology.
Grant type:
ARC Discovery Projects
Researchers:
  • Professorial Research Fellow - Grou
    Institute for Molecular Bioscience
    Professorial Research Fellow - Grou
    Institute for Molecular Bioscience
    Affiliate Professor of School of Ch
    School of Chemistry and Molecular Biosciences
    Faculty of Science
    Affiliate of ARC COE for Innovation
    ARC Centre of Excellence for Innovations in Peptide and Protein Science
    Institute for Molecular Bioscience
  • Senior Research Fellow
    Institute for Molecular Bioscience
    Senior Research Fellow
    Institute for Molecular Bioscience
  • NHMRC Leadership Fellow - Group Lea
    Institute for Molecular Bioscience
    NHMRC Leadership Fellow - Group Lea
    School of Pharmacy
    Faculty of Health and Behavioural Sciences
    NHMRC Leadership Fellow - Group Lea
    Institute for Molecular Bioscience
Funded by:
Australian Research Council