Insights into protein modifications by NMR (2019–2021)
Abstract:
The aim of this project is to understand how the modifications that occur in proteins during cancer processes change
their structure and function. I aim to develop novel methodologies at the interface of protein chemistry and structural
biology that will generate new knowledge and influence therapeutic design. Applying chemical protein synthesis
techniques will enable me to introduce desired modifications and specific sites for structural studies at atomic resolution
using nuclear magnetic resonance spectroscopy. My contributions in the teaching capacity area will further benefit my
career prospects and training of the next generation of scientists at UQ.