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Cross-kingdom communications via small non-coding RNAs (2015–2017)

Abstract:
Small non-coding RNAs play significant roles in various biological processes, including host-microorganism interactions. Recent evidence suggests that small RNAs can be exchanged between microorganisms and their hosts and regulate gene expression in the other organism. The endosymbiotic bacterium, Wolbachia, has attracted worldwide attention due to inhibiting replication of various vector-borne pathogens in mosquito vectors. This proposal will determine the role of small non-coding RNAs in mosquito-Wolbachia interactions, including Wolbachia microRNAs, concentrating on exchanged microRNAs between the two organisms and explore their effect on Wolbachia maintenance and its anti-viral property.
Grant type:
ARC Discovery Projects
Researchers:

  • Professor Sassan Asgari

    Professor
    School of the Environment
    Faculty of Science
    Professor
    School of the Environment
    Faculty of Science
    of School of Chemistry and Molecula
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council