OR

Browse By

High Speed Fluorescence Imaging coupled with Total Internal Reflection Microscopy and Fluorescence Recovery After Photobleaching System (2008–2009)

Abstract:
This proposal is for a Total Internal Reflection Flueorescence imaging system that will allow direct visualisation of intramolecular events and transient protein-protein interactions occurring on a millisecond time scale in living cells. The equipment will include a photo-ablation system allowing the powerful combination of imaging techniques, which will provide unprecedented insight into the dynamics of plasma membrane proteins and their mobility. This will enable researchers in cellular and neuronal biology to access sophisticated technology to pioneer their research. Understanding of the dynamics of protein and organelles and the molecular interactions underlying organelle fusion will have wide-ranging ramifications in disease treatment.
Grant type:
ARC Linkage Infrastructure, Equipment and Facilities
Researchers:

  • Professor Frederic Meunier

    Professor and Academic Senior Group
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    Affiliate Professor of Institute fo
    Institute for Molecular Bioscience

  • Professor Jennifer Stow

    NHMRC Leadership Fellow
    Institute for Molecular Bioscience
    NHMRC Leadership Fellow
    Institute for Molecular Bioscience
    Affiliate of ARC COE in Quantum Bio
    ARC Centre of Excellence in Quantum Biotechnology
    Faculty of Science

  • Professor Robert Parton

    ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    Affiliate Professor
    School of Biomedical Sciences
    Faculty of Medicine

  • Associate Professor Peter Noakes

    Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine

  • Professor Elizabeth Coulson

    Head of School
    School of Biomedical Sciences
    Faculty of Medicine
    Head of School
    Faculty of Medicine
    Professor
    Queensland Brain Institute
    Professor and Professorial Research
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    Head of School of Biomedical Scienc
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
Australian Research Council