OR

Browse By

Structural analysis of membrane proteins using template-mediated crystallization (2005–2007)

Abstract:
Membrane proteins comprise 25-40% of all proteins and conduct a myriad of finely tuned reactions in every cell. The clear rate-limiting step in structure determination of membrane proteins in particular is the production of high quality crystals for electron and X-ray crystallography. The aim of this project is to develop a new systematic template-mediated membrane protein crystallization process using a lipid layer strategy. This approach is well suited for the crystallization of a wide range of membrane proteins including those that are small hydrophobic glycosylated and recalcitrant to traditional methods of 3D crystal production
Grant type:
ARC Discovery Projects
Researchers:

  • Professor Ben Hankamer

    Professorial Research Fellow
    Institute for Molecular Bioscience
    Professorial Research Fellow
    Institute for Molecular Bioscience
    Affiliate Professor of School of Ch
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council