The University of Queensland

Live molecular imaging using super resolution microscopy, two photon and spinning disk confocal microscopy (2013–2014)

Abstract:

A new era of molecular live imaging has begun which allows rapid 3-D visualisation of biological processes such as brain wiring in vivo down to the tracking of a single molecule. This relies on recent advances in imaging including multiphoton, spinning-disk and particularly super-resolution microscopy. The goal of this application is to establish the first multi-instrument super-resolution system in Queensland, allowing a team of multi-institutional cross-disciplinary researchers to use these emerging technologies to image single molecules within the cellular environment in living cells. Such insight is key to understanding basical biological interactions that govern brain wiring, communication between cells, and cell-cell adhesion.

Grant type:

ARC Linkage Infrastructure, Equipment and Facilities

Researchers:

• 

  Professor Frederic Meunier

  Professor and Academic Snr Gp Lead
  

  Queensland Brain Institute

• 

  Professor Alpha Yap

  Professor and ARC Laureate Fellow
  

  Institute for Molecular Bioscience

• 

  Professor Halina Rubinsztein-Dunlop

  Professor
  

  School of Mathematics and Physics

  Faculty of Science

  Affiliate Professor
  

  Australian Institute for Bioengineering and Nanotechnology

Funded by:

Australian Research Council