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Live molecular imaging using super resolution microscopy, two photon and spinning disk confocal microscopy (2013–2014)

Abstract:
A new era of molecular live imaging has begun which allows rapid 3-D visualisation of biological processes such as brain wiring in vivo down to the tracking of a single molecule. This relies on recent advances in imaging including multiphoton, spinning-disk and particularly super-resolution microscopy. The goal of this application is to establish the first multi-instrument super-resolution system in Queensland, allowing a team of multi-institutional cross-disciplinary researchers to use these emerging technologies to image single molecules within the cellular environment in living cells. Such insight is key to understanding basical biological interactions that govern brain wiring, communication between cells, and cell-cell adhesion.
Grant type:
ARC Linkage Infrastructure, Equipment and Facilities
Researchers:

  • Professor Frederic Meunier

    Professor and Academic Senior Group
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    Affiliate Professor of Institute fo
    Institute for Molecular Bioscience

  • Professor Alpha Yap

    Professor and ARC Laureate Fellow
    Institute for Molecular Bioscience
    Affiliate Professor of School of Bi
    School of Biomedical Sciences
    Faculty of Medicine

  • Professor Halina Rubinsztein-Dunlop

    Professor
    School of Mathematics and Physics
    Faculty of Science
    Professor
    School of Mathematics and Physics
    Faculty of Science
    Affiliate of ARC COE in Quantum Bio
    ARC Centre of Excellence in Quantum Biotechnology
    Faculty of Science
    Affiliate of ARC COE for Engineered
    ARC Centre of Excellence for Engineered Quantum Systems
    Faculty of Science
    Affiliate Professor
    Australian Institute for Bioengineering and Nanotechnology
Funded by:
Australian Research Council