Defining the molecular mechanisms of intracellular protein trafficking (2011–2014)

Abstract:
Intracellular transport of biomolecules is critical for normal cellular processes such as signaling, neurosecretion and development. Defects in these fundamental processes or subversion by pathogens also lead to many debilitating human diseases. This project will build on Australia's strong program of structural and cellular biology research to develop fundamental insights into how protein machineries control dynamic intracellular trafficking with such exquisite selectivity, with important implications for future design of pharmaceuticals aimed at inhibiting or enhancing these systems.
Grant type:
ARC Future Fellowships
Researchers:
  • NHMRC Leadership Fellow - GL
    Institute for Molecular Bioscience
    NHMRC Leadership Fellow - GL
    Institute for Molecular Bioscience
    of Institute for Molecular Bioscien
    Institute for Molecular Bioscience
    Affiliate Professor of School of Bi
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
Australian Research Council