Dynamics of constrained Brownian motion of neuro-secretory vesicles. (2011–2013)
- Abstract:
- Despite years of research on brain cell communication, the sequence of molecular events leading a neuron to release its neurotransmitter is far from understood. The interactions underpinning this process are highly dependent on the microenvironment surrounding the vesicles containing the neurotransmitter which has been notoriously hard to assess. We will bridge this gap using new optical methods to simultaneously track active and passive motion of such vesicles to allow full modelling of the vesicle transport and assess for the first time the viscoelastic properties of their immediate microenvironment . This work will give valuable new clues to finally solve the dynamics of molecular interactions underpinning neuronal communication.
- Grant type:
- ARC Discovery Projects
- Researchers:
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Professor
School of Mathematics and PhysicsFaculty of ScienceProfessor
School of Mathematics and PhysicsFaculty of ScienceAffiliate of ARC COE in Quantum Bio
ARC Centre of Excellence in Quantum BiotechnologyFaculty of ScienceAffiliate of ARC COE for Engineered
ARC Centre of Excellence for Engineered Quantum SystemsFaculty of ScienceAffiliate Professor
Australian Institute for Bioengineering and Nanotechnology -
Senior Lecturer
School of Mathematics and PhysicsFaculty of ScienceSenior Lecturer
School of Mathematics and PhysicsFaculty of Science -
Professor and Academic Senior Group
Queensland Brain Instituteof Clem Jones Centre for Ageing and
Clem Jones Centre for Ageing Dementia ResearchQueensland Brain Instituteof Clem Jones Centre for Ageing and
Clem Jones Centre for Ageing Dementia ResearchQueensland Brain InstituteAffiliate Professor of Institute fo
Institute for Molecular Bioscience
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- Funded by:
- Australian Research Council
