Myosin VI: a novel molecular apparatus for epithelial cohesion. (2010–2012)

Adhesion between cells holds the human body together and affects many aspects of our health including normal tissue and organ function. Conversely, loss of normal cell-cell adhesion contributes to major diseases, including cancer and inflammation. One key molecule, E-cadherin, is necessary for many epithelial organs and its function is perturbed in disease. This research project addresses how E-cadherin works with a cellular motor, Myosin VI, to maintain the integrity of epithelial tissues.
Grant type:
NHMRC Project Grant
  • Professor and ARC Laureate Fellow
    Institute for Molecular Bioscience
  • NHMRC Leadership Fellow - GL
    Institute for Molecular Bioscience
  • ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    Affiliate Professor
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
National Health and Medical Research Council