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Control of neurosecretion by Munc18 (2010–2012)

Abstract:
Neuronal communication relies on the process of exocytosis by which neurons release a neurotransmitter. Exocytosis is critical for the simplest muscle movement to complex tasks such as learning and memory, and is altered in several neurodegenerative pathologies. We will investigate how the protein Munc18 controls exocytosis. This research will be important for understanding how neurons communicate in health and disease and will be relevant to other processes such as insulin release in diabetes.
Grant type:
NHMRC Project Grant
Researchers:

  • Professor Frederic Meunier

    Professor and Academic Senior Group
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    Affiliate Professor of Institute fo
    Institute for Molecular Bioscience

  • Professor Brett Collins

    NHMRC Leadership Fellow - GL
    Institute for Molecular Bioscience
    NHMRC Leadership Fellow - GL
    Institute for Molecular Bioscience
    of Institute for Molecular Bioscien
    Institute for Molecular Bioscience
    Affiliate Professor of School of Bi
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
National Health and Medical Research Council