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New peptide-based drugs for the treatment of neuropathic pain (2010–2012)

Abstract:
Chronic pain affects 1 in 5 Australians and neuropathic pain is among the most severe forms of chronic pain. Peptides from cone snail venoms have attracted recent attention as potential therapeutic agents for the treatment of neuropathic pain. Unfortunately, these peptides suffer from the disadvantage of short biological half-lives and poor activity when taken orally. We have developed a new approach to solve these problems that we will apply to develop new drugs for the treatment of pain.
Grant type:
NHMRC Project Grant
Researchers:

  • Professor David Craik

    UQ Laureate Fellow - GL
    Institute for Molecular Bioscience
    UQ Laureate Fellow - GL
    Institute for Molecular Bioscience
    Centre Director of ARC COE for Inno
    ARC Centre of Excellence for Innovations in Peptide and Protein Science
    Institute for Molecular Bioscience
    Affiliate Professor of School of Bi
    School of Biomedical Sciences
    Faculty of Medicine

  • Associate Professor Richard Clark

    Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Affiliate Associate Professor of In
    Institute for Molecular Bioscience
Funded by:
National Health and Medical Research Council