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Caveolin-1 and the formation of new blood vessels (2009–2010)

Abstract:
To grow and spread, tumors need to be supplied with blood. Preventing the formation of new blood vessels represents a highly promising improvement of cancer treatment. We have shown that the distribution of caveolin-1 is uneven in cells that migrate to initiate new capillaries. We will determine the mechanisms and consequences of this uneven distribution. This will improve our understanding of tumor blood vessel formation and provide the basis for development of new anti cancer treatments.
Grant type:
National Heart Foundation of Australia
Researchers:

  • Associate Professor Marie-Odile Parat

    Associate Professor
    School of Pharmacy
    Faculty of Health and Behavioural Sciences

  • Professor Robert Parton

    ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    Affiliate Professor
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
National Heart Foundation of Australia