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Interstitially Invasive Trophoblast of the Murine Placenta: Developmental Origins, Functions and Gene Expression. (2009–2012)

Abstract:
Due to the obvious limitations to studying human pregnancy, the mouse has become a valuable model. However, invasion of the placenta into the uterine wall and vasculature, critical for successful pregnancy, is poorly understood in the mouse. The aims of the proposal are designed to gain a better understanding of these processes in mice and will provide a more accurate model system to study serious pregnancy complications resulting from abnormal placental invasion, such as preeclampsia.
Grant type:
NHMRC Project Grant
Researchers:

  • Dr David Simmons

    Senior Lec in Developmental Biology
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
National Health and Medical Research Council